Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy
Completed
Lexicon Pharmaceuticals
Phase 2
2009-03-01
The purpose of this study is to evaluate the safety and tolerability of telotristat etiprate
(LX1606) versus a placebo control in participants with symptomatic carcinoid syndrome not
managed by stable-dose long-acting octreotide therapy. Following determination of the
maximally tolerated or effective dose, cohort expansion will occur to confirm effect on
symptoms and safety profile.
Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome
Completed
Lexicon Pharmaceuticals
Phase 2
2010-06-15
The purpose of the study is to evaluate the safety and tolerability of orally administered
telotristat etiprate (LX1606) in participants with symptomatic carcinoid syndrome.
A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to Moderate Ulcerative Colitis
Completed
Lexicon Pharmaceuticals
Phase 2
2012-01-30
This is a multicenter, placebo-controlled, parallel-group, pilot study to evaluate safety and
preliminary effectiveness of two blinded dose levels of telotristat etiprate (LX1606) in
participants with acute, mild to moderate ulcerative colitis on 5-aminosalicylic
acid/mesalamine therapy.
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