An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension
Completed
Novartis Pharmaceuticals
Phase 2
2013-04-01
The main purpose of this exploratory study was to investigate the effect of serelaxin
(RLX030) infusion on the hepatic and renal circulation in patients with compensated cirrhosis
and portal hypertension. Measurements were acquired non-invasively using magnetic resonance
angiography (MRA) (study part A) and more directly via cannulation of the hepatic portal vein
during a routine transjugular intrahepatic portosystemic shunt (TIPSS) check procedure (study
part B), to determine the acute haemodynamic response to serelaxin (RLX030).
Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1
Completed
Watermark
Phase 3
2016-07-13
This study is to treat adult patients with hepatorenal syndrome (HRS) Type 1.
Out of every three participants, two will receive terlipressin and one will receive placebo.
Assignments will be made randomly.
Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1
Completed
Mallinckrodt
Phase 3
2016-07-13
This study is to treat adult patients with hepatorenal syndrome (HRS) Type 1.
Out of every three participants, two will receive terlipressin and one will receive placebo.
Assignments will be made randomly.
Effect of Terlipressin on Cerebral Oxygen Saturation During Liver Transplantation
Completed
Kasr El Aini Hospital
Phase 2
2018-01-25
in our study the investigators aim to assess the effect of terlipressin on cerebral
oxygenation monitored by cerebral oxymetry and cerebral blood flow measured by transcranial
doppler.
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