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Last Updated: November 5, 2024

CLINICAL TRIALS PROFILE FOR THORAZINE


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All Clinical Trials for THORAZINE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01231074 ↗ Reducing Antipsychotic-Induced Weight Gain in Children With Metformin Completed Nationwide Children's Hospital Phase 1 2010-02-01 Recent but limited short term studies have shown that Metformin can slow down weight gain in obese children and in children with psychotropic-induced weight gain, two distinct pediatric populations that are at risk for obesity related co-morbid conditions. The purpose of this study is to conduct a long term prospective pilot cohort study to investigate the use of Metformin to prevent or decrease weight gain in two cohorts of children: 1) children with psychotropic induced weight gain on Metformin and 2) children with BMI above the 95th percentile on Metformin. Both study populations will be enrolled in a lifestyle weight management program
NCT03021486 ↗ Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer Active, not recruiting National Cancer Institute (NCI) Phase 2/Phase 3 2017-06-05 This randomized phase II/III trial studies how well haloperidol with or without chlorpromazine works in treating delirium in patients with cancer that has spread to other parts of the body or has come back. Haloperidol and chlorpromazine may control the symptoms of delirium (loss of contact with reality) in patients with cancer.
NCT03021486 ↗ Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer Active, not recruiting National Institute of Nursing Research (NINR) Phase 2/Phase 3 2017-06-05 This randomized phase II/III trial studies how well haloperidol with or without chlorpromazine works in treating delirium in patients with cancer that has spread to other parts of the body or has come back. Haloperidol and chlorpromazine may control the symptoms of delirium (loss of contact with reality) in patients with cancer.
NCT03021486 ↗ Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer Active, not recruiting National Institutes of Health (NIH) Phase 2/Phase 3 2017-06-05 This randomized phase II/III trial studies how well haloperidol with or without chlorpromazine works in treating delirium in patients with cancer that has spread to other parts of the body or has come back. Haloperidol and chlorpromazine may control the symptoms of delirium (loss of contact with reality) in patients with cancer.
NCT03021486 ↗ Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer Active, not recruiting M.D. Anderson Cancer Center Phase 2/Phase 3 2017-06-05 This randomized phase II/III trial studies how well haloperidol with or without chlorpromazine works in treating delirium in patients with cancer that has spread to other parts of the body or has come back. Haloperidol and chlorpromazine may control the symptoms of delirium (loss of contact with reality) in patients with cancer.
NCT04224441 ↗ Repurposing Chlorpromazine in the Treatment of Glioblastoma Recruiting Carlo Besta Neurological Institute Phase 2 2019-12-15 This study evaluates the addition of chlorpromazine to the first-line therapeutic protocol, i.e. maximal well-tolerated surgical resection followed by radiotherapy plus concomitant and adjuvant chemotherapy with temozolomide, in newly diagnosed glioblastoma multiforme patients carrying a hypo-methylated O6-methylguanine-DNA-methyltransferase (MGMT) gene
NCT04224441 ↗ Repurposing Chlorpromazine in the Treatment of Glioblastoma Recruiting Istituto Oncologico Veneto IRCCS Phase 2 2019-12-15 This study evaluates the addition of chlorpromazine to the first-line therapeutic protocol, i.e. maximal well-tolerated surgical resection followed by radiotherapy plus concomitant and adjuvant chemotherapy with temozolomide, in newly diagnosed glioblastoma multiforme patients carrying a hypo-methylated O6-methylguanine-DNA-methyltransferase (MGMT) gene
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for THORAZINE

Condition Name

Condition Name for THORAZINE
Intervention Trials
Glioblastoma Multiforme 2
Obesity 1
Psychotropic Induced Weight Gain 1
Recurrent Malignant Neoplasm 1
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Condition MeSH

Condition MeSH for THORAZINE
Intervention Trials
Glioblastoma 2
Neoplasms 1
Delirium 1
Weight Gain 1
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Clinical Trial Locations for THORAZINE

Trials by Country

Trials by Country for THORAZINE
Location Trials
Italy 3
United States 3
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Trials by US State

Trials by US State for THORAZINE
Location Trials
Iowa 1
Texas 1
Ohio 1
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Clinical Trial Progress for THORAZINE

Clinical Trial Phase

Clinical Trial Phase for THORAZINE
Clinical Trial Phase Trials
Phase 2/Phase 3 1
Phase 2 1
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for THORAZINE
Clinical Trial Phase Trials
Completed 1
Not yet recruiting 1
Recruiting 1
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Clinical Trial Sponsors for THORAZINE

Sponsor Name

Sponsor Name for THORAZINE
Sponsor Trials
Carlo Besta Neurological Institute 1
Istituto Oncologico Veneto IRCCS 1
Regina Elena Cancer Institute 1
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Sponsor Type

Sponsor Type for THORAZINE
Sponsor Trials
Other 7
NIH 3
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