CLINICAL TRIALS PROFILE FOR TIKOSYN
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All Clinical Trials for TIKOSYN
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00392106 ↗ | High Intensity Focused Ultrasound (HIFU) Ablation System Study | Suspended | ProRhythm, Inc. | Phase 3 | 2006-04-01 | The purpose of this study is to determine if the HIFU Pulmonary Vein Ablation System is effective in the treatment of paroxysmal Atrial Fibrillation compared to the control of best medical therapy with FDA approved antiarrhythmic drugs. |
| NCT00589303 ↗ | AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study | Terminated | Medtronic | Phase 3 | 2007-12-01 | The purpose of this study is to determine whether early atrioventricular node (AVN) ablation with pacing device therapy will reduce death and hospitalization when compared to the conventional drug therapy in elderly patients with recurrent and symptomatic atrial fibrillation (AF). |
| NCT00589303 ↗ | AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study | Terminated | Mayo Clinic | Phase 3 | 2007-12-01 | The purpose of this study is to determine whether early atrioventricular node (AVN) ablation with pacing device therapy will reduce death and hospitalization when compared to the conventional drug therapy in elderly patients with recurrent and symptomatic atrial fibrillation (AF). |
| NCT02308748 ↗ | Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block | Completed | Spaulding Clinical Research LLC | Phase 1 | 2014-05-01 | The primary objective of this research study is to test the hypothesis that late sodium current blocking drugs (mexiletine or lidocaine) can attenuate the effect of hERG potassium channel blocking drugs (dofetilide) on ventricular repolarization (QTc) by shortening early repolarization (J-Tpeakc). The secondary object is to assess the ability of calcium channel block (diltiazem) to reduce the QTc prolongation associated with hERG block (moxifloxacin). |
| NCT02308748 ↗ | Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block | Completed | Food and Drug Administration (FDA) | Phase 1 | 2014-05-01 | The primary objective of this research study is to test the hypothesis that late sodium current blocking drugs (mexiletine or lidocaine) can attenuate the effect of hERG potassium channel blocking drugs (dofetilide) on ventricular repolarization (QTc) by shortening early repolarization (J-Tpeakc). The secondary object is to assess the ability of calcium channel block (diltiazem) to reduce the QTc prolongation associated with hERG block (moxifloxacin). |
| NCT02439658 ↗ | Genetics of QT Prolongation With Antiarrhythmics | Recruiting | Beth Israel Deaconess Medical Center | 2014-01-01 | To assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being loaded with dofetilide or sotalol. | |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for TIKOSYN
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