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Last Updated: December 22, 2024

CLINICAL TRIALS PROFILE FOR TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

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All Clinical Trials for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01955837 ↗	Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in Asia	Completed	Taiho Pharmaceutical Co., Ltd.	Phase 3	2013-09-01	To compare the effects of TAS-102 with placebo in patients with metastatic colorectal cancer refractory or intolerable to standard chemotherapies.
NCT02654639 ↗	Ph 2 Study of TAS-102 / Bevacizumab Maintenance Therapy Post Induction Chemotherapy in Metastatic Colorectal Cancer	Terminated	Georgetown University	Phase 2	2016-02-01	Phase II study of TAS-102 plus bevacizumab switch maintenance therapy in patients with mCRC
NCT03278106 ↗	TAS-102 in Treating Advanced Biliary Tract Cancers	Active, not recruiting	National Cancer Institute (NCI)	Phase 2	2017-10-20	This phase II trial studies how well trifluridine/tipiracil hydrochloride combination agent TAS-102 (TAS-102) works in treating participants with biliary tract cancers that have spread to other places in the body. Drugs used in the chemotherapy, such as trifluridine/tipiracil hydrochloride combination agent TAS-102, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
NCT03278106 ↗	TAS-102 in Treating Advanced Biliary Tract Cancers	Active, not recruiting	Mayo Clinic	Phase 2	2017-10-20	This phase II trial studies how well trifluridine/tipiracil hydrochloride combination agent TAS-102 (TAS-102) works in treating participants with biliary tract cancers that have spread to other places in the body. Drugs used in the chemotherapy, such as trifluridine/tipiracil hydrochloride combination agent TAS-102, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

Condition Name

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Condition Name for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Intervention	Trials
Metastatic Colorectal Cancer	12
Colorectal Cancer	7
Stage IVC Colorectal Cancer AJCC v8	6
Stage IV Colorectal Cancer AJCC v8	6
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Condition MeSH

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Condition MeSH for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Intervention	Trials
Colorectal Neoplasms	39
Adenocarcinoma	17
Colonic Neoplasms	8
Carcinoma	8
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Clinical Trial Locations for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

Trials by Country

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Trials by Country for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Location	Trials
United States	111
Italy	28
China	25
Japan	18
Australia	11
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Trials by US State

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Trials by US State for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Location	Trials
California	10
Florida	8
Texas	8
Minnesota	8
Arizona	8
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Clinical Trial Progress for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

Clinical Trial Phase

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Clinical Trial Phase for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Clinical Trial Phase	Trials
Phase 3	11
Phase 2	33
Phase 1/Phase 2	5
[disabled in preview]	8
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Clinical Trial Status

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Clinical Trial Status for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Clinical Trial Phase	Trials
Recruiting	27
Not yet recruiting	14
Active, not recruiting	6
[disabled in preview]	3
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Clinical Trial Sponsors for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE

Sponsor Name

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Sponsor Name for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Sponsor	Trials
National Cancer Institute (NCI)	14
Servier	4
Mayo Clinic	4
[disabled in preview]	4
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Sponsor Type

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Sponsor Type for TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
Sponsor	Trials
Other	55
Industry	30
NIH	14
[disabled in preview]	0
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.