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Last Updated: November 5, 2024

CLINICAL TRIALS PROFILE FOR VANIQA


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All Clinical Trials for VANIQA

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00601640 ↗ Eflornithine and/or Diclofenac in Treating Patients With Sun-Damaged Skin Completed National Cancer Institute (NCI) Phase 2 2007-01-01 RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of eflornithine and diclofenac may stop cancer from growing in patients with sun-damaged skin. PURPOSE: This randomized phase II trial is studying the side effects and how well eflornithine works compared with diclofenac, given alone or together, in treating patients with sun-damaged skin.
NCT00601640 ↗ Eflornithine and/or Diclofenac in Treating Patients With Sun-Damaged Skin Completed University of Arizona Phase 2 2007-01-01 RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of eflornithine and diclofenac may stop cancer from growing in patients with sun-damaged skin. PURPOSE: This randomized phase II trial is studying the side effects and how well eflornithine works compared with diclofenac, given alone or together, in treating patients with sun-damaged skin.
NCT01817894 ↗ Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism Completed Bispebjerg Hospital Phase 4 2012-01-01 Split-face investigation of the efficacy of applying Eflornithin cream twice daily for six months after a period with six laser treatments for hair removal.
NCT03794349 ↗ Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Active, not recruiting National Cancer Institute (NCI) Phase 2 2019-05-28 This phase II trial studies how well irinotecan hydrochloride, temozolomide, and dinutuximab work with or without eflornithine in treating patients with neuroblastoma that has come back (relapsed) or that isn't responding to treatment (refractory). Drugs used in chemotherapy, such as irinotecan hydrochloride and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as dinutuximab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Eflornithine blocks the production of chemicals called polyamines that are important in the growth of cancer cells. Giving eflornithine with irinotecan hydrochloride, temozolomide, and dinutuximab, may work better in treating patients with relapsed or refractory neuroblastoma.
NCT03794349 ↗ Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Active, not recruiting Children's Oncology Group Phase 2 2019-05-28 This phase II trial studies how well irinotecan hydrochloride, temozolomide, and dinutuximab work with or without eflornithine in treating patients with neuroblastoma that has come back (relapsed) or that isn't responding to treatment (refractory). Drugs used in chemotherapy, such as irinotecan hydrochloride and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as dinutuximab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Eflornithine blocks the production of chemicals called polyamines that are important in the growth of cancer cells. Giving eflornithine with irinotecan hydrochloride, temozolomide, and dinutuximab, may work better in treating patients with relapsed or refractory neuroblastoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for VANIQA

Condition Name

Condition Name for VANIQA
Intervention Trials
Ganglioneuroblastoma 1
High Risk Neuroblastoma 1
Hirsutism 1
Non-melanomatous Skin Cancer 1
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Condition MeSH

Condition MeSH for VANIQA
Intervention Trials
Neuroblastoma 1
Ganglioneuroblastoma 1
Hirsutism 1
Skin Neoplasms 1
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Clinical Trial Locations for VANIQA

Trials by Country

Trials by Country for VANIQA
Location Trials
United States 44
Canada 5
Australia 5
New Zealand 2
Denmark 1
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Trials by US State

Trials by US State for VANIQA
Location Trials
Nevada 1
Nebraska 1
Missouri 1
Mississippi 1
Minnesota 1
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Clinical Trial Progress for VANIQA

Clinical Trial Phase

Clinical Trial Phase for VANIQA
Clinical Trial Phase Trials
Phase 4 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for VANIQA
Clinical Trial Phase Trials
Completed 2
Active, not recruiting 1
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Clinical Trial Sponsors for VANIQA

Sponsor Name

Sponsor Name for VANIQA
Sponsor Trials
National Cancer Institute (NCI) 2
University of Arizona 1
Bispebjerg Hospital 1
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Sponsor Type

Sponsor Type for VANIQA
Sponsor Trials
Other 3
NIH 2
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