Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults
Completed
AIDS Clinical Trials Group
N/A
2003-10-01
HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy
the virus in these cells. Enfuvirtide, also known as T-20, is a type of anti-HIV drug called
a fusion inhibitor. The purpose of this study is to test the ability of a T-20-enhanced
treatment regimen to decrease the number of resting CD4 cells that become infected with HIV.
Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults
Completed
National Institute of Allergy and Infectious Diseases (NIAID)
N/A
2003-10-01
HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy
the virus in these cells. Enfuvirtide, also known as T-20, is a type of anti-HIV drug called
a fusion inhibitor. The purpose of this study is to test the ability of a T-20-enhanced
treatment regimen to decrease the number of resting CD4 cells that become infected with HIV.
Preventing Sexual Transmission of HIV With Anti-HIV Drugs
Completed
HIV Prevention Trials Network
Phase 3
2005-02-01
This study will determine whether anti-HIV drugs can prevent the sexual transmission of HIV
among couples in which one partner is HIV infected and the other is not.
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