Fasting Study of Metolazone Tablets 2.5 mg and Zaroloxyn® Tablets 2.5 mg
Completed
Mylan Pharmaceuticals
Phase 1
2002-12-01
The objective of this study was to investigate the bioequivalence of Mylan metolazone 2.5 mg
tablets to Celltech Zaroxolyn® 2.5 mg tablets following a single, oral 10 mg (4 x 2.5 mg)
dose administration under fasting conditions.
Fasting Study of Metolazone Tablets 5 mg and Zaroloxyn® Tablets 5 mg
Completed
Mylan Pharmaceuticals
Phase 1
2003-10-01
The objective of this study was to investigate the bioequivalence of Mylan metolazone 5 mg
tablets to Celltech Zaroxolyn® 5 mg tablets following a single, oral 10 mg (2 x 5 mg) dose
administration under fasting conditions.
Fasting Study of Metolazone Tablets 10 mg and Zaroloxyn® Tablets 10 mg
Completed
Mylan Pharmaceuticals
Phase 1
2004-02-01
The objective of this study was to investigate the bioequivalence of Mylan metolazone 10 mg
tablets to Celltech Zaroxolyn® 10 mg tablets following a single, oral 10 mg (1 x 10 mg) dose
administration under fasting conditions.
Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure
Terminated
University of Illinois at Chicago
Phase 4
2008-10-01
The purpose of this prospective, randomized, open-label study is to compare two diuretic
strategies in patients with acute decompensated heart failure (ADHF): the addition of an oral
thiazide diuretic to intravenous bolus (IVB) loop diuretic will be compared to transition
from IVB to continuous infusion (CI) loop diuretic.
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