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Last Updated: November 23, 2024

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CLINICAL TRIALS PROFILE FOR ZOLINZA


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All Clinical Trials for ZOLINZA

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00121225 ↗ Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma Completed National Cancer Institute (NCI) Phase 2 2005-09-01 This phase II trial is studying how well vorinostat works in treating patients with metastatic or unresectable melanoma. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
NCT00127101 ↗ An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED) Terminated Merck Sharp & Dohme Corp. Phase 1 2005-09-01 This is an investigational study that increases the dosage to determine the safety/tolerability, and efficacy of a histone deacetylase inhibitor in combination with Targretin in patients with cutaneous T-cell lymphoma in patients who have failed at least one prior systemic therapy.
NCT00128102 ↗ Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) Versus Placebo in Advanced Malignant Pleural Mesothelioma (MK-0683-014) Completed Merck Sharp & Dohme Corp. Phase 3 2005-06-30 The goal of this study is to assess the efficacy and safety of an oral investigational drug suberoylanilide hydroxamic acid (vorinostat, MK-0683) compared to placebo, in the treatment of participants with advanced malignant pleural mesothelioma who have failed at least one prior chemotherapy regimen. The primary hypotheses are the following: (1) vorinostat improves overall survival (OS) compared to placebo (2) vorinostat is generally safe and well tolerated.
NCT00132002 ↗ Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer Terminated National Cancer Institute (NCI) Phase 2 2005-06-01 This phase II trial is studying how well suberoylanilide hydroxamic acid works in treating patients with progressive stage IV breast cancer. Drugs used in chemotherapy, such as suberoylanilide hydroxamic acid, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Suberoylanilide hydroxamic acid may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ZOLINZA

Condition Name

Condition Name for ZOLINZA
Intervention Trials
Lymphoma 11
Unspecified Adult Solid Tumor, Protocol Specific 10
Recurrent Adult Acute Myeloid Leukemia 10
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) 8
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Condition MeSH

Condition MeSH for ZOLINZA
Intervention Trials
Lymphoma 35
Leukemia 26
Lymphoma, Non-Hodgkin 21
Leukemia, Myeloid, Acute 20
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Clinical Trial Locations for ZOLINZA

Trials by Country

Trials by Country for ZOLINZA
Location Trials
United States 545
Canada 33
Australia 8
Japan 6
Germany 2
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Trials by US State

Trials by US State for ZOLINZA
Location Trials
Texas 43
California 35
Pennsylvania 30
New York 27
Maryland 25
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Clinical Trial Progress for ZOLINZA

Clinical Trial Phase

Clinical Trial Phase for ZOLINZA
Clinical Trial Phase Trials
Phase 3 3
Phase 2/Phase 3 2
Phase 2 53
[disabled in preview] 35
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Clinical Trial Status

Clinical Trial Status for ZOLINZA
Clinical Trial Phase Trials
Completed 91
Terminated 30
Active, not recruiting 21
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Clinical Trial Sponsors for ZOLINZA

Sponsor Name

Sponsor Name for ZOLINZA
Sponsor Trials
National Cancer Institute (NCI) 81
Merck Sharp & Dohme Corp. 39
M.D. Anderson Cancer Center 19
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Sponsor Type

Sponsor Type for ZOLINZA
Sponsor Trials
Other 165
NIH 86
Industry 63
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