CLINICAL TRIALS PROFILE FOR AMPHETAMINE
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505(b)(2) Clinical Trials for amphetamine
| Trial Type | Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|---|
| New Indication | NCT01189214 ↗ | Psychopharmacotherapy in Multiple Substances Abuse | Completed | National Institutes of Health (NIH) | Phase 3 | 2009-03-01 | Add-on of memantine or placebo treatment will proceed in a double-blinded fashion for 12 weeks after adjusted methadone dose. During the study, the investigators will evaluate treatment response and adverse effect from multiple dimensions to elucidate the therapeutic effect of add-on memantine on addictive behaviors. It will also explore the possible advantage of this treatment on social re-adaptation and psychopathogenesis of opioid dependence. |
| New Indication | NCT01189214 ↗ | Psychopharmacotherapy in Multiple Substances Abuse | Completed | National Cheng-Kung University Hospital | Phase 3 | 2009-03-01 | Add-on of memantine or placebo treatment will proceed in a double-blinded fashion for 12 weeks after adjusted methadone dose. During the study, the investigators will evaluate treatment response and adverse effect from multiple dimensions to elucidate the therapeutic effect of add-on memantine on addictive behaviors. It will also explore the possible advantage of this treatment on social re-adaptation and psychopathogenesis of opioid dependence. |
| OTC | NCT01736332 ↗ | Factors Affecting Methamphetamine and Opiates Drug Testing | Completed | National Institute on Drug Abuse (NIDA) | Phase 1 | 2012-07-19 | Background: - Some legal over-the-counter drugs (such as Vicks VapoInhaler ) and some foods (such as poppy seeds) may cause a positive screening drug test. This might look like someone used illegal drugs (such as methamphetamines or opiates) when they did not. Researchers are studying how the body handles chemicals that may test like illegal drugs and for how long they may be detected in the body. Blood, saliva, and urine samples will be collected. This study may help improve the effectiveness and accuracy of drug tests. Objectives: - To see how the body handles chemicals that may produce positive screening tests and how additional testing can eliminate positive drug tests from over-the-counter drugs and food. Eligibility: - Healthy volunteers between 18 and 65 years of age. Design: - Participants are screened with a physical exam, medical history, laboratory tests, and ECG. - This study involves an overnight stay on a secure research unit and 2 days of tests. - On the first day, participants will take Vicks VapoInhaler (two inhalations in each nostril) every 2 hours from 9 a.m. to 7 p.m. They will also take a drink containing poppy seeds twice (at about 9 a.m. and 5 p.m.). - On the morning of the second day, participants will take the Vicks VapoInhaler just once. They will be discharged around 5 p.m. - On both days, participants will provide blood and saliva samples several times throughout the day. All of their urine will be collected during the 2 study days.... |
| >Trial Type | >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
All Clinical Trials for amphetamine
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00000305 ↗ | Amphetamine Cocaine Interaction Study - 2 | Terminated | National Institute on Drug Abuse (NIDA) | Phase 1 | 1969-12-31 | The purpose of this study is to evaluate results of d-amphetamine - cocaine (pharmacology) interaction study. |
| NCT00000305 ↗ | Amphetamine Cocaine Interaction Study - 2 | Terminated | University of Texas | Phase 1 | 1969-12-31 | The purpose of this study is to evaluate results of d-amphetamine - cocaine (pharmacology) interaction study. |
| NCT00000305 ↗ | Amphetamine Cocaine Interaction Study - 2 | Terminated | The University of Texas Health Science Center, Houston | Phase 1 | 1969-12-31 | The purpose of this study is to evaluate results of d-amphetamine - cocaine (pharmacology) interaction study. |
| NCT00000308 ↗ | Dextroamphetamine-Cocaine Behavioral Intervention - 5 | Completed | University of Texas | Phase 2 | 1995-09-01 | The purpose of this study is to examine dextroamphetamine-cocaine behavioral intervention in cocaine dependent patients. |
| NCT00000308 ↗ | Dextroamphetamine-Cocaine Behavioral Intervention - 5 | Completed | National Institute on Drug Abuse (NIDA) | Phase 2 | 1995-09-01 | The purpose of this study is to examine dextroamphetamine-cocaine behavioral intervention in cocaine dependent patients. |
| NCT00000347 ↗ | Risperidone for Treatment of Cocaine Dependence in Outpatients - 12 | Completed | National Institute on Drug Abuse (NIDA) | Phase 2 | 1997-07-01 | The purpose of this study is to evaluate pharmacological efficacy and clinical safety of risperidone in the treatment of cocaine and amphetamine dependence. |
| NCT00001783 ↗ | Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 | 1998-04-01 | The purpose of this study is to determine if giving amphetamines along with standard rehabilitation speeds motor recovery after a stroke. In addition, if motor recovery is improved, the study will also identify the areas of the brain involved with the recovery. Researchers will use motor function ratings, PET scans, functional MRI (fMRI), electroencephalographs, and transcranial magnetic stimulation (TMS) to evaluate patients. Patients participating in the study will be placed in one of two groups; 1. Patients receiving dextroamphetamine and routine Rehabilitation Medicine 2. Patients receiving a placebo "sugar pill" and routine Rehabilitation Medicine Patients that have improved motor recovery will undergo neuroimaging and neurophysiological studies to identify areas of the brain involved. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for amphetamine
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