CLINICAL TRIALS PROFILE FOR ATOVAQUONE; PROGUANIL HYDROCHLORIDE
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All Clinical Trials for atovaquone; proguanil hydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00084227 ↗ | Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America | Completed | Pfizer | Phase 2/Phase 3 | 2004-07-01 | The primary objective is to confirm the hypothesis that azithromycin plus chloroquine is non-inferior to atovaquone-proguanil for the treatment of symptomatic, uncomplicated malaria due to P. falciparum. |
| NCT00149383 ↗ | Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria | Completed | McLaughlin-Rotman Center for Global Health, University of Toronto | Phase 1/Phase 2 | 2004-12-01 | The purpose of this study is to examine the safety, tolerability, and efficacy of adjunctive rosiglitazone in the treatment of uncomplicated P.falciparum malaria. |
| NCT00149383 ↗ | Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria | Completed | Mahidol University | Phase 1/Phase 2 | 2004-12-01 | The purpose of this study is to examine the safety, tolerability, and efficacy of adjunctive rosiglitazone in the treatment of uncomplicated P.falciparum malaria. |
| NCT00379821 ↗ | Chloroquine Alone or in Combination for Malaria in Children in Malawi | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 3 | 2007-02-01 | Malaria is a sickness caused by a germ that can get into a person's body when a mosquito bites them. It can cause fever, headache, body aches and weakness. It can even cause death, especially in children. When malaria is treated with the appropriate medicine(s), it can be cured completely. The purpose of this study is to find out if it is better to use chloroquine alone or in combination with another drug to most effectively treat malaria. About 640 children with malaria, aged 6 months to 5 years of age, from the Blantyre Malaria Project Research Clinic at the Ndirande Health Center in Malawi will be in the study. They will be treated with either chloroquine alone or a combination of chloroquine plus another medication (azithromycin or artesunate or atovaquone-proguanil) every time they get malaria for a year. Blood samples will be collected and tested at least every 4 weeks. Participants will be involved in the study for 1 year. |
| NCT00386750 ↗ | Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function | Terminated | Novartis Pharmaceuticals | Phase 4 | 2005-06-01 | THIS STUDY IS NOT ENROLLING PATIENTS IN THE USA. To evaluate the effects of artemether/ lumefantrine on the auditory function. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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