Effects of Epinephrine and Intravenous (I.V.) Needle on Cardiopulmonary Resuscitation (CPR) Outcome
Completed
Health Region East, Norway
Phase 2
2003-01-01
Intravenous epinephrine has been part of the guidelines for cardiopulmonary resuscitation
since the start. It improves outcome in animal studies, but has never been investigated in a
controlled study in humans. Epidemiologic data indicate that it is an independent negative
predictor for survival. If this is true in a controlled randomized study, it could be due to
effects of the drug itself or more likely due to reduced quality of chest compressions and
ventilations due to the time spent on placing an I.V. needle and injecting drugs.
Effects of Epinephrine and Intravenous (I.V.) Needle on Cardiopulmonary Resuscitation (CPR) Outcome
Completed
Laerdal Medical
Phase 2
2003-01-01
Intravenous epinephrine has been part of the guidelines for cardiopulmonary resuscitation
since the start. It improves outcome in animal studies, but has never been investigated in a
controlled study in humans. Epidemiologic data indicate that it is an independent negative
predictor for survival. If this is true in a controlled randomized study, it could be due to
effects of the drug itself or more likely due to reduced quality of chest compressions and
ventilations due to the time spent on placing an I.V. needle and injecting drugs.
Effects of Epinephrine and Intravenous (I.V.) Needle on Cardiopulmonary Resuscitation (CPR) Outcome
Completed
Norwegian Air Ambulance Foundation
Phase 2
2003-01-01
Intravenous epinephrine has been part of the guidelines for cardiopulmonary resuscitation
since the start. It improves outcome in animal studies, but has never been investigated in a
controlled study in humans. Epidemiologic data indicate that it is an independent negative
predictor for survival. If this is true in a controlled randomized study, it could be due to
effects of the drug itself or more likely due to reduced quality of chest compressions and
ventilations due to the time spent on placing an I.V. needle and injecting drugs.
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