Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Recruiting
Cristália Produtos Químicos Farmacêuticos Ltda.
Phase 3
2018-01-31
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Recruiting
University of Sao Paulo
Phase 3
2018-01-31
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Recruiting
Federal University of São Paulo
Phase 3
2018-01-31
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
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