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Last Updated: December 22, 2024

CLINICAL TRIALS PROFILE FOR BUPROPION HYDROCHLORIDE; NALTREXONE HYDROCHLORIDE


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All Clinical Trials for bupropion hydrochloride; naltrexone hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00129246 ↗ Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain Completed National Institute on Alcohol Abuse and Alcoholism (NIAAA) Phase 1/Phase 2 2004-12-01 This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
NCT00129246 ↗ Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain Completed Yale University Phase 1/Phase 2 2004-12-01 This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
NCT00208169 ↗ Abilify Therapy for Reducing Comorbid Substance Abuse Completed Bristol-Myers Squibb Phase 4 2005-03-01 It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole.
NCT00208169 ↗ Abilify Therapy for Reducing Comorbid Substance Abuse Completed Creighton University Phase 4 2005-03-01 It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole.
NCT00364871 ↗ Efficacy and Safety Study of Combination Therapy to Treat Uncomplicated Obesity Completed Orexigen Therapeutics, Inc Phase 2 2005-04-01 The purpose of this study is to determine the efficacy and safety of 3 combinations of naltrexone and bupropion SR compared to naltrexone alone, bupropion SR alone or placebo.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for bupropion hydrochloride; naltrexone hydrochloride

Condition Name

Condition Name for bupropion hydrochloride; naltrexone hydrochloride
Intervention Trials
Obesity 25
Overweight 8
Binge-eating Disorder 5
Schizophrenia 3
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Condition MeSH

Condition MeSH for bupropion hydrochloride; naltrexone hydrochloride
Intervention Trials
Overweight 15
Obesity 12
Disease 7
Feeding and Eating Disorders 6
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Clinical Trial Locations for bupropion hydrochloride; naltrexone hydrochloride

Trials by Country

Trials by Country for bupropion hydrochloride; naltrexone hydrochloride
Location Trials
United States 241
Canada 2
Korea, Republic of 1
Greece 1
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Trials by US State

Trials by US State for bupropion hydrochloride; naltrexone hydrochloride
Location Trials
Connecticut 15
California 13
Texas 11
Ohio 10
South Carolina 9
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Clinical Trial Progress for bupropion hydrochloride; naltrexone hydrochloride

Clinical Trial Phase

Clinical Trial Phase for bupropion hydrochloride; naltrexone hydrochloride
Clinical Trial Phase Trials
Phase 4 12
Phase 3 7
Phase 2/Phase 3 9
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Clinical Trial Status

Clinical Trial Status for bupropion hydrochloride; naltrexone hydrochloride
Clinical Trial Phase Trials
Completed 23
Recruiting 8
Not yet recruiting 5
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Clinical Trial Sponsors for bupropion hydrochloride; naltrexone hydrochloride

Sponsor Name

Sponsor Name for bupropion hydrochloride; naltrexone hydrochloride
Sponsor Trials
Orexigen Therapeutics, Inc 15
Yale University 12
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 6
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Sponsor Type

Sponsor Type for bupropion hydrochloride; naltrexone hydrochloride
Sponsor Trials
Other 40
Industry 22
NIH 14
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