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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR CAPMATINIB HYDROCHLORIDE


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All Clinical Trials for capmatinib hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01610336 ↗ A Safety and Efficacy Study of INC280 and Gefitinib in Patients With EGFR Mutated, c-MET-amplified NSCLC Who Have Progressed After EGFRi Treatment Completed Novartis Pharmaceuticals Phase 2 2012-04-05 This study assessed the safety and efficacy of escalating doses INC280 when added to gefitinib in patients with lung cancer that were known to have dysregulation of the c-MET pathway and who had failed after benefiting on a prior treatment with either gefitinib or erlotinib.
NCT02587650 ↗ Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma Terminated Adil Daud Phase 2 2015-03-26 This phase II trial studies how well capmatinib, ceritinib, regorafenib, or entrectinib work in treating patients with BRAF/NRAS wild-type stage III-IV melanoma. Capmatinib, ceritinib, regorafenib, or entrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02587650 ↗ Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma Terminated University of California, San Francisco Phase 2 2015-03-26 This phase II trial studies how well capmatinib, ceritinib, regorafenib, or entrectinib work in treating patients with BRAF/NRAS wild-type stage III-IV melanoma. Capmatinib, ceritinib, regorafenib, or entrectinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02750215 ↗ A Study of Capmatinib (INC280) in NSCLC Patients With MET Exon 14 Alterations Who Have Received Prior MET Inhibitor Completed Novartis Phase 2 2016-05-01 This research study is studying capmatinib as a treatment for advanced non-small cell lung cancer with MET exon 14 skipping, where the participant has already received prior therapy with a MET inhibitor.
NCT02750215 ↗ A Study of Capmatinib (INC280) in NSCLC Patients With MET Exon 14 Alterations Who Have Received Prior MET Inhibitor Completed Massachusetts General Hospital Phase 2 2016-05-01 This research study is studying capmatinib as a treatment for advanced non-small cell lung cancer with MET exon 14 skipping, where the participant has already received prior therapy with a MET inhibitor.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for capmatinib hydrochloride

Condition Name

Condition Name for capmatinib hydrochloride
Intervention Trials
Carcinoma, Non-Small-Cell Lung 5
Non-small Cell Lung Cancer 3
Melanoma 2
Non-Small Cell Lung Cancer (NSCLC) 2
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Condition MeSH

Condition MeSH for capmatinib hydrochloride
Intervention Trials
Carcinoma, Non-Small-Cell Lung 15
Lung Neoplasms 9
Carcinoma 3
Melanoma 2
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Clinical Trial Locations for capmatinib hydrochloride

Trials by Country

Trials by Country for capmatinib hydrochloride
Location Trials
Spain 27
United States 25
Italy 17
China 15
Germany 10
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Trials by US State

Trials by US State for capmatinib hydrochloride
Location Trials
Massachusetts 5
California 5
New York 3
Texas 2
Pennsylvania 2
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Clinical Trial Progress for capmatinib hydrochloride

Clinical Trial Phase

Clinical Trial Phase for capmatinib hydrochloride
Clinical Trial Phase Trials
Phase 4 1
Phase 3 3
Phase 2 18
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Clinical Trial Status

Clinical Trial Status for capmatinib hydrochloride
Clinical Trial Phase Trials
Not yet recruiting 9
Recruiting 8
Completed 3
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Clinical Trial Sponsors for capmatinib hydrochloride

Sponsor Name

Sponsor Name for capmatinib hydrochloride
Sponsor Trials
Novartis Pharmaceuticals 14
Novartis 4
Assistance Publique - Hôpitaux de Paris 1
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Sponsor Type

Sponsor Type for capmatinib hydrochloride
Sponsor Trials
Industry 21
Other 19
NIH 1
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