Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Completed
National Cancer Institute (NCI)
Phase 2
2003-06-01
RATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in
children with cancer.
PURPOSE: This phase II trial is studying how well cyproheptadine and megestrol work in
improving appetite and preventing weight loss in children with cachexia caused by cancer or
cancer treatment.
Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Completed
University of South Florida
Phase 2
2003-06-01
RATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in
children with cancer.
PURPOSE: This phase II trial is studying how well cyproheptadine and megestrol work in
improving appetite and preventing weight loss in children with cachexia caused by cancer or
cancer treatment.
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
Completed
US Department of Veterans Affairs
Phase 4
2003-10-01
The purpose of this study is to determine whether prazosin will reduce the incidence of
nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with
PTSD.
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
Completed
VA Office of Research and Development
Phase 4
2003-10-01
The purpose of this study is to determine whether prazosin will reduce the incidence of
nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with
PTSD.
Topiramate for the Prophylactic Treatment of Cyclic Vomiting Syndrome in Children
Terminated
Ortho-McNeil Neurologics, Inc.
Phase 4
2006-03-01
The purpose of this study is to assess the effectiveness, tolerability and safety of oral
topiramate for the preventative management of Cyclic Vomiting Syndrome. It is believed that
topiramate will decrease the frequency, duration and severity of attacks experienced by
children and adolescents with Cyclic Vomiting Syndrome.
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