Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
Completed
Children's Hospital of Philadelphia
N/A
1998-05-01
OBJECTIVES: I. Confirm the inhibitory effect of recombinant human insulin-like growth factor
I (IGF-I) on insulin secretion in children with hyperinsulinism.
II. Define the effects of short term IGF-I therapy on postprandial blood sugar levels in this
patient population.
III. Characterize the effects of short term IGF-I therapy on fasting behavior, and other
insulin dependent parameters, in this patient population.
Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
Completed
FDA Office of Orphan Products Development
N/A
1998-05-01
OBJECTIVES: I. Confirm the inhibitory effect of recombinant human insulin-like growth factor
I (IGF-I) on insulin secretion in children with hyperinsulinism.
II. Define the effects of short term IGF-I therapy on postprandial blood sugar levels in this
patient population.
III. Characterize the effects of short term IGF-I therapy on fasting behavior, and other
insulin dependent parameters, in this patient population.
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