CLINICAL TRIALS PROFILE FOR ENALAPRILAT
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All Clinical Trials for enalaprilat
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00226096 ↗ | Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage | Completed | National Health and Medical Research Council, Australia | N/A | 2005-11-01 | The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving with a long term disability. The study will be undertaken in two phases: a vanguard phase in 400 patients, to plan for a main phase in 2000 patients. |
| NCT00226096 ↗ | Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage | Completed | The George Institute | N/A | 2005-11-01 | The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving with a long term disability. The study will be undertaken in two phases: a vanguard phase in 400 patients, to plan for a main phase in 2000 patients. |
| NCT00741156 ↗ | The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution | Completed | The Hospital for Sick Children | Phase 3 | 2008-07-01 | The primary objective of this study is to study the acute effects of angiotensin-converting enzyme inhibitor (ACEI) on systemic, pulmonary and cerebral blood flow in post bidirectional cavopulmonary connection (BCPC) patients. |
| NCT01324245 ↗ | Intervention Study to Compare the Natriuretic Effects of Enalapril on Low and High Salt Diet | Completed | University of Virginia | N/A | 2002-11-01 | The kidney plays a crucial role in maintaining salt balance by two opposing physiological mechanisms: the renal dopaminergic system which enhances salt excretion and the renin-angiotensin system (RAS) which causes salt retention. Salt-sensitive hypertension occurs when this balance is altered or abnormal. We hypothesized that this balance is influenced by salt intake: therefore dietary salt affects the natriuretic response to the renal dopaminergic agonist Fenoldopam, and the Angiotensin Converting Enzyme inhibitor, Enalapril. In this trial we study normal salt balance mechanisms in salt resistant adults with normal blood pressure. |
| NCT01324245 ↗ | Intervention Study to Compare the Natriuretic Effects of Enalapril on Low and High Salt Diet | Completed | Georgetown University | N/A | 2002-11-01 | The kidney plays a crucial role in maintaining salt balance by two opposing physiological mechanisms: the renal dopaminergic system which enhances salt excretion and the renin-angiotensin system (RAS) which causes salt retention. Salt-sensitive hypertension occurs when this balance is altered or abnormal. We hypothesized that this balance is influenced by salt intake: therefore dietary salt affects the natriuretic response to the renal dopaminergic agonist Fenoldopam, and the Angiotensin Converting Enzyme inhibitor, Enalapril. In this trial we study normal salt balance mechanisms in salt resistant adults with normal blood pressure. |
| NCT01413542 ↗ | Pharmacogenetics of Ace Inhibitor-Associated Angioedema | Completed | Vanderbilt University | N/A | 2011-11-01 | The investigators would like to find out if sitagliptin (dipeptidyl peptidase-4 or DPP4 inhibition), a drug to treat diabetes, affects blood vessel relaxation in healthy people receiving enalapril (angiotensin converting enzyme or ACE inhibition), a blood pressure medicine. Understanding how these drugs interact in healthy people will help us learn their potential effects in people who have diabetes. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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