Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Unknown status
Cosmozone Dental Clinic
N/A
2015-01-01
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative
recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is
at its peak in the first 12 hours. Our study evaluates if the use of 2% lidocaine
hydrochloride for the surgical removal of lower third molars with a postoperative 0.5%
bupivacaine supplementation would result in lesser postoperative pain and a decrease in
ingestion of oral analgesics to control the pain when compared to a placebo.
The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The
repair of such lacerations is usually done using a pre-existing epidural analgesia. Once the
analgesic effect of the epidural analgesia fades, the laceration may cause intolerable pain,
and result in emotional stress, difficulties in ambulation and breastfeeding, and more.
The research team hypothesis is that adding a locally injected analgesic, which will take
effect once the epidural analgesia fades, may alleviate perineal pain, prevent such
difficulties, and improve women's overall well-being and satisfaction.
The proposed trial is a two-arm, single-masked, randomized trial. Women with a working
epidural analgesia, and a laceration will be invited to participate. Women in the local
anesthesia (LA) arm will get a LA injected to the laceration and women in the sham arm will
get no injection. The differences in perineal pain between the groups will be evaluated at 6
hours after last epidural dose.
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