CLINICAL TRIALS PROFILE FOR ESTAZOLAM

All Clinical Trials for estazolam

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00347295 ↗	Randomised, Double-blind Study to Investigate the Safety and Efficacy of Brotizolam in Insomnia Outpatients.	Completed	Boehringer Ingelheim	Phase 3	2006-06-01	To investigate the efficacy and safety of Brotizolam in the treatment of patients with insomnia in comparison with that of Estazolam
NCT00956319 ↗	A Study to Evaluate Efficacy and Safety of Zolpidem Modified Release Formulation in Insomnia Patients	Completed	Astellas Pharma Inc	Phase 4	2009-05-01	The purpose of the study is to investigate the efficacy and safety of zolpidem modified release (MR) tablet using estazolam (Eurodin) as a comparative drug in patients with primary insomnia.
NCT03708341 ↗	Exogenous Melatonin in Intensive Care Unit Chronodisruption	Unknown status	Saint-Joseph University	Phase 3	2018-11-15	To this day, a small number of studies have evaluated the effect of melatonin on the modifications of the characteristics of sleep in critical care units, with mostly a small studied population. However, no study has been realized on a large population, nor has it evaluated the association between genetic factors and response to treatment (melatonin), hence the originality of our study. In our study we hypothesized that systematic melatonin usage in ICU can ameliorate the total sleep time and the fragmentation index and can decrease the confusion related to sleep deprivation.
NCT03997058 ↗	Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD	Active, not recruiting	Haitao Tu	Phase 4	2019-03-01	Maintenance hemodialysis (MHD) is one of the most important treatments for patients with end-stage renal failure. Studies have found that insomnia is widespread in MHD patients, affecting their quality of life. Auricular acupoint pressing is an effective traditional Chinese medicine treatment for insomnia. This study compared the effects of auricular acupoint pressing and oral estazolam on insomnia in patients with MHD, and evaluated the possibility of auricular acupoint pressing to reduce the incidence of adverse events by improving insomnia in patients with MHD, and to explore the insomnia of MHD patients treated with TCM characteristics. The role and efficacy provide a basis for the treatment of sleep disorders by Chinese medicine.
NCT03997058 ↗	Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD	Active, not recruiting	The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine	Phase 4	2019-03-01	Maintenance hemodialysis (MHD) is one of the most important treatments for patients with end-stage renal failure. Studies have found that insomnia is widespread in MHD patients, affecting their quality of life. Auricular acupoint pressing is an effective traditional Chinese medicine treatment for insomnia. This study compared the effects of auricular acupoint pressing and oral estazolam on insomnia in patients with MHD, and evaluated the possibility of auricular acupoint pressing to reduce the incidence of adverse events by improving insomnia in patients with MHD, and to explore the insomnia of MHD patients treated with TCM characteristics. The role and efficacy provide a basis for the treatment of sleep disorders by Chinese medicine.
NCT05452577 ↗	Treatment of Chronic Insomnia According to Yin Yang Theory and Its Correlation With Circadian Rhythm	Recruiting	The First Affiliated Hospital with Nanjing Medical University	N/A	2021-01-22	The purpose of this study is to assess the safety and efficacy of Traditional Chinese medicine (TCM) according to Yin Yang theory for treatment of chronic insomnia .

Clinical Trial Conditions for estazolam

Condition Name

Condition Name for estazolam
Intervention	Trials
Sleep Initiation and Maintenance Disorders	3
Intensive Care Psychosis	1
Primary Insomnia	1
Renal Dialysis	1

Condition MeSH

Condition MeSH for estazolam
Intervention	Trials
Sleep Initiation and Maintenance Disorders	4
Mental Disorders	1
Sleep Deprivation	1
Psychotic Disorders	1

Clinical Trial Locations for estazolam

Trials by Country

Trials by Country for estazolam
Location	Trials
China	3
Lebanon	1
Taiwan	1

Clinical Trial Progress for estazolam

Clinical Trial Phase

Clinical Trial Phase for estazolam
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	2
N/A	1

Clinical Trial Status

Clinical Trial Status for estazolam
Clinical Trial Phase	Trials
Completed	2
Recruiting	1
Unknown status	1

Clinical Trial Sponsors for estazolam

Sponsor Name

Sponsor Name for estazolam
Sponsor	Trials
Boehringer Ingelheim	1
Astellas Pharma Inc	1
Saint-Joseph University	1

Sponsor Type

Sponsor Type for estazolam
Sponsor	Trials
Other	4
Industry	2