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Last Updated: December 26, 2024

CLINICAL TRIALS PROFILE FOR ETIDRONATE DISODIUM


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All Clinical Trials for etidronate disodium

Trial ID Title Status Sponsor Phase Start Date Summary
NCT05662111 ↗ Treatment of Ectopic Calcification in Fahr's Disease or Syndrome Not yet recruiting Netherlands Brain Foundation Phase 2 2023-02-01 Fahr's disease or syndrome are neurodegenerative diseases in which patients present with bilateral vessel associated calcifications in the basal ganglia. The clinical penetration of Fahr's disease or syndrome is incomplete and heterogeneous comprising of neuropsychiatric signs, cognitive decline, movement disorders, and various other signs (migraine, speech disorders, pain, seizures). The symptoms start between 30 and 50 years and are (slowly) progressive. Symptomatic patients have an increased risk for dependence in activities of daily living and impaired quality of life. Currently, disease-modifying therapies are not available for patients with Fahr's disease or syndrome. However, in a small case series it was shown that alendronate was effective in the clinical treatment of several patients with Fahr's disease or syndrome. Now the time has come to investigate the effectiveness of treatment with bisphosphonates in patients with Fahr's disease or syndrome in a randomized controlled trial.
NCT05662111 ↗ Treatment of Ectopic Calcification in Fahr's Disease or Syndrome Not yet recruiting UMC Utrecht Phase 2 2023-02-01 Fahr's disease or syndrome are neurodegenerative diseases in which patients present with bilateral vessel associated calcifications in the basal ganglia. The clinical penetration of Fahr's disease or syndrome is incomplete and heterogeneous comprising of neuropsychiatric signs, cognitive decline, movement disorders, and various other signs (migraine, speech disorders, pain, seizures). The symptoms start between 30 and 50 years and are (slowly) progressive. Symptomatic patients have an increased risk for dependence in activities of daily living and impaired quality of life. Currently, disease-modifying therapies are not available for patients with Fahr's disease or syndrome. However, in a small case series it was shown that alendronate was effective in the clinical treatment of several patients with Fahr's disease or syndrome. Now the time has come to investigate the effectiveness of treatment with bisphosphonates in patients with Fahr's disease or syndrome in a randomized controlled trial.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for etidronate disodium

Condition Name

Condition Name for etidronate disodium
Intervention Trials
Fahr Disease 1
Fahr Syndrome 1
Primary Familial Brain Calcification 1
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Condition MeSH

Condition MeSH for etidronate disodium
Intervention Trials
Syndrome 1
Calcinosis 1
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Clinical Trial Progress for etidronate disodium

Clinical Trial Phase

Clinical Trial Phase for etidronate disodium
Clinical Trial Phase Trials
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for etidronate disodium
Clinical Trial Phase Trials
Not yet recruiting 1
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Clinical Trial Sponsors for etidronate disodium

Sponsor Name

Sponsor Name for etidronate disodium
Sponsor Trials
Netherlands Brain Foundation 1
UMC Utrecht 1
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Sponsor Type

Sponsor Type for etidronate disodium
Sponsor Trials
Other 2
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