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Last Updated: March 31, 2025

CLINICAL TRIALS PROFILE FOR FLURBIPROFEN SODIUM


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All Clinical Trials for flurbiprofen sodium

Trial IDTitleStatusSponsorPhaseStart DateSummary
NCT02017197 ↗ Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil Completed Fundação de Amparo à Pesquisa do Estado de São Paulo Phase 4 2014-08-01 The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT02017197 ↗ Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil Completed Federal University of São Paulo Phase 4 2014-08-01 The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT02569905 ↗ Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering Completed Guangxi Medical University Phase 4 2014-04-01 Shivering is an early postoperative complication during the postoperative recovery period, and there is no clear consensus about the best way for its prevention. The aim of the study was to compare the efficacy and accompanying side effects of prophylactic flurbiprofen with that of parecoxib or placebo for reducing postoperative shivering.
>Trial ID>Title>Status>Phase>Start Date>Summary
Showing 1 to 3 of 3 entries

Clinical Trial Conditions for flurbiprofen sodium

Condition Name

110-0.100.10.20.30.40.50.60.70.80.911.1Atrial FibrillationPostoperative Shivering[disabled in preview]
Condition Name for flurbiprofen sodium
Intervention Trials
Atrial Fibrillation 1
Postoperative Shivering 1
[disabled in preview] 0
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Condition MeSH

10-0.100.10.20.30.40.50.60.70.80.911.1Atrial Fibrillation[disabled in preview]
Condition MeSH for flurbiprofen sodium
Intervention Trials
Atrial Fibrillation 1
[disabled in preview] 0
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Clinical Trial Locations for flurbiprofen sodium

Trials by Country

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Trials by Country for flurbiprofen sodium
Location Trials
Brazil 1
China 1
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Clinical Trial Progress for flurbiprofen sodium

Clinical Trial Phase

100.0%0-0.200.20.40.60.811.21.41.61.822.2Phase 4[disabled in preview]
Clinical Trial Phase for flurbiprofen sodium
Clinical Trial Phase Trials
Phase 4 2
[disabled in preview] 0
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Clinical Trial Status

100.0%0-0.200.20.40.60.811.21.41.61.822.2Completed[disabled in preview]
Clinical Trial Status for flurbiprofen sodium
Clinical Trial Phase Trials
Completed 2
[disabled in preview] 0
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Clinical Trial Sponsors for flurbiprofen sodium

Sponsor Name

trials000001111111Fundação de Amparo à Pesquisa do Estado de São PauloFederal University of São PauloGuangxi Medical University[disabled in preview]
Sponsor Name for flurbiprofen sodium
Sponsor Trials
Fundação de Amparo à Pesquisa do Estado de São Paulo 1
Federal University of São Paulo 1
Guangxi Medical University 1
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Sponsor Type

100.0%000.511.522.53Other[disabled in preview]
Sponsor Type for flurbiprofen sodium
Sponsor Trials
Other 3
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Flurbiprofen Sodium: Clinical Trials, Market Analysis, and Projections

Introduction

Flurbiprofen sodium, a nonsteroidal anti-inflammatory drug (NSAID), is widely used for its analgesic, anti-inflammatory, and antipyretic properties. This article delves into recent clinical trials, market analysis, and future projections for this drug.

Clinical Trials Update

Efficacy in Rheumatoid Arthritis

A clinical trial conducted to assess the variability in response to flurbiprofen in patients with rheumatoid arthritis showed promising results. Patients were treated with flurbiprofen 100 mg three times a day, and the outcomes included pain relief and a Ritchie articular index of joint tenderness. The study found significant improvements in both pain relief and articular tenderness, with no evidence to support the concept of responders and non-responders[1].

Perioperative Analgesia

A systematic review and Bayesian network meta-analysis evaluated the efficacy and safety of flurbiprofen axetil for perioperative analgesia in children. The study included 49 randomized controlled trials involving 3,657 patients and compared flurbiprofen axetil with placebo or other standard treatments. The results indicated that flurbiprofen axetil was effective in reducing postoperative pain scores and had a favorable safety profile compared to other analgesics[4].

Market Analysis

Global Market Size and Growth

The global flurbiprofen market has experienced significant growth and is projected to continue this trend. According to market research, the global flurbiprofen market size was estimated at USD XX million in 2024 and is expected to grow at a compound annual growth rate (CAGR) of 5.2% from 2024 to 2031[2][3].

Regional Market Dynamics

North America

North America holds the largest share of the global flurbiprofen market, accounting for more than 40% of the global revenue. The market in this region is driven by the high prevalence of musculoskeletal disorders, arthritis, and inflammatory conditions. The dominant segment in North America is flurbiprofen injections, which provide rapid and potent relief from pain and inflammation[2].

Europe

Europe accounts for over 30% of the global market size. The aging population in Europe significantly contributes to the demand for pain management solutions like flurbiprofen. The patch segment is dominant in this region, offering continuous and site-specific pain relief, particularly for conditions like osteoarthritis[2].

Asia Pacific

The Asia Pacific region holds around 23% of the global revenue and is expected to grow at a CAGR of 7.2% from 2024 to 2031. This growth is driven by rapid urbanization, improving healthcare infrastructure, and increasing awareness of pain management. The injection segment is dominant in this region, with ongoing developments in innovative formulations and injection technologies[2].

South America and Middle East & Africa

In South America, the market is expected to grow at a CAGR of 4.6%, driven by the rising prevalence of musculoskeletal disorders and inflammatory conditions. The patch segment is gaining traction as a non-invasive alternative to traditional oral medications. In the Middle East and Africa, the market will grow at a CAGR of 4.9%, fueled by the development of healthcare infrastructure and an increasing focus on pain management[2].

Market Segmentation

By Formulation

The flurbiprofen market is segmented into injections, patches, and tablets. Injections are particularly valuable in acute and severe conditions, while patches offer continuous and site-specific pain relief. Tablets are used for general pain management and inflammatory conditions[3].

By Application

Flurbiprofen is used in various applications, including nonsteroidal anti-inflammatory drugs, topical administration for joint and muscle pain, soft tissue disease, dysmenorrhea, post-operative pain, toothache, and other pain-related conditions. The diverse range of applications contributes to the drug's widespread use and market growth[3].

Market Drivers and Challenges

Drivers

  • Aging Population: The increasing age of the global population contributes significantly to the demand for pain management solutions.
  • Prevalence of Musculoskeletal Disorders: Conditions such as arthritis and inflammatory diseases drive the need for effective pain relief medications.
  • Advancements in Formulations: Innovations in injection technologies and patch formulations enhance the efficacy and convenience of flurbiprofen[2][3].

Challenges

  • Regulatory Complexities: Navigating diverse regulatory landscapes, especially in regions like Europe and the Asia Pacific, poses a challenge for market entry and expansion.
  • Economic Disparities: Addressing economic disparities and adapting to diverse healthcare systems is crucial for success in regions like Latin America and the Middle East & Africa[2][3].

Future Projections

The flurbiprofen market is poised for significant growth due to the increasing demand for pain management solutions. Here are some key projections:

  • Global Growth: The market is expected to grow at a CAGR of 5.2% from 2024 to 2031, driven by the factors mentioned above[2][3].
  • Regional Expansion: Asia Pacific is expected to be the fastest-growing region, with a CAGR of 7.2%, followed by other regions with steady growth rates[2].
  • Innovative Formulations: Continued advancements in formulations, particularly in injections and patches, will further drive market growth and penetration[2][3].

Key Takeaways

  • Clinical Efficacy: Flurbiprofen has shown significant efficacy in clinical trials for rheumatoid arthritis and perioperative analgesia.
  • Market Growth: The global flurbiprofen market is projected to grow at a CAGR of 5.2% from 2024 to 2031.
  • Regional Dynamics: North America, Europe, and Asia Pacific are key regions driving market growth, each with dominant segments such as injections and patches.
  • Market Drivers: The aging population, prevalence of musculoskeletal disorders, and advancements in formulations are major drivers of the market.
  • Challenges: Regulatory complexities and economic disparities need to be addressed for sustained market growth.

FAQs

What is the current market size of the global flurbiprofen market?

The global flurbiprofen market size was estimated at USD XX million in 2024[2].

What is the projected CAGR for the global flurbiprofen market from 2024 to 2031?

The global flurbiprofen market is expected to grow at a CAGR of 5.2% from 2024 to 2031[2][3].

Which region is expected to be the fastest-growing for the flurbiprofen market?

The Asia Pacific region is expected to be the fastest-growing, with a CAGR of 7.2% from 2024 to 2031[2].

What are the dominant segments in the North American and European flurbiprofen markets?

In North America, the dominant segment is flurbiprofen injections, while in Europe, it is the patch segment[2].

What are the main drivers of the flurbiprofen market?

The main drivers include the aging population, prevalence of musculoskeletal disorders, and advancements in formulations[2][3].

Sources

  1. Variability in response to nonsteroidal anti-inflammatory analgesics - PubMed
  2. Flurbiprofen Market Report - Cognitive Market Research
  3. Global Flurbiprofen Market Size, Scope And Forecast Report - Market Research Intellect
  4. Efficacy and safety of parecoxib and flurbiprofen axetil for perioperative analgesia in children - Frontiers in Medicine
  5. Sodium Flurbiprofen Market Size, Share, Trend and Forecast - Prof Research

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