Agitation affects 70 to 90 percent of patients with AD. Signs of agitation include verbal and
physical aggressiveness, irritability, wandering, and restlessness. These behaviors often
make caring for patients at home very difficult. Trazodone and haldol are two of the most
commonly prescribed drugs for agitation in AD patients. Behavior management, a non drug
approach, has been effective in reducing signs of agitation. Researchers have yet to compare
the effectiveness of drug versus non drug therapy to treat agitation in AD patients and
determine which is the best treatment. The Alzheimer's Disease Cooperative Study, with
funding from the National Institute on Aging, is conducting an agitation treatment program at
21 sites in 16 States. This study will assess which of the above treatments is most
effective.
Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9
Completed
New York State Psychiatric Institute
Phase 2
1997-03-01
The purpose of this study is to evaluate the safety and efficacy of flupenthixol and
haloperidol for cocaine dependence in individuals with schizophrenia/schizoaffective illness.
Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9
Completed
National Institute on Drug Abuse (NIDA)
Phase 2
1997-03-01
The purpose of this study is to evaluate the safety and efficacy of flupenthixol and
haloperidol for cocaine dependence in individuals with schizophrenia/schizoaffective illness.
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