CLINICAL TRIALS PROFILE FOR HEXAMINOLEVULINATE HYDROCHLORIDE
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All Clinical Trials for hexaminolevulinate hydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00052637 ↗ | Cystoscopy and Hexyl 5-Aminolevulinate in Detecting Carcinoma In Situ in Patients With Bladder Cancer | Completed | National Cancer Institute (NCI) | Phase 3 | 2001-09-01 | RATIONALE: Diagnostic procedures such as cystoscopy may improve the ability to detect cancer and to determine the extent of disease. PURPOSE: Diagnostic trial to compare the effectiveness of cystoscopy using hexyl 5-aminolevulinate and two light sources in detecting carcinoma in situ in patients who have bladder cancer. |
| NCT00052637 ↗ | Cystoscopy and Hexyl 5-Aminolevulinate in Detecting Carcinoma In Situ in Patients With Bladder Cancer | Completed | Photocure | Phase 3 | 2001-09-01 | RATIONALE: Diagnostic procedures such as cystoscopy may improve the ability to detect cancer and to determine the extent of disease. PURPOSE: Diagnostic trial to compare the effectiveness of cystoscopy using hexyl 5-aminolevulinate and two light sources in detecting carcinoma in situ in patients who have bladder cancer. |
| NCT00285701 ↗ | Early Detection of Polyps and Colon Cancer by Fluorescence Imaging - a Dose-finding Study | Completed | KARL STORZ Endoscopy-America, Inc. | Phase 1/Phase 2 | 2006-07-01 | Patients referred for colon inspection (colonoscopy) due to suspicion of colon polyps/cancer will receive local administration of hexaminolevulinate (HAL) prior to colon inspection. Blue light illumination will induce red fluorescence of polyps and tumours, improving detection of the polyps and tumors. Different HAL doses will be tested to find the optimal image conditions. Tolerability measurements will be performed to ensure patient safety. |
| NCT00285701 ↗ | Early Detection of Polyps and Colon Cancer by Fluorescence Imaging - a Dose-finding Study | Completed | Photocure | Phase 1/Phase 2 | 2006-07-01 | Patients referred for colon inspection (colonoscopy) due to suspicion of colon polyps/cancer will receive local administration of hexaminolevulinate (HAL) prior to colon inspection. Blue light illumination will induce red fluorescence of polyps and tumours, improving detection of the polyps and tumors. Different HAL doses will be tested to find the optimal image conditions. Tolerability measurements will be performed to ensure patient safety. |
| NCT00369018 ↗ | A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions. | Completed | Photocure | Phase 1/Phase 2 | 2006-08-01 | The study will determine the best drug (MAL or HAL) dosage for photodynamic therapy of cervical precancerous lesions (dysplasia) in women that are referred for conisation (surgery). |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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