Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)
Completed
Geron Corporation
Phase 1
2005-07-01
The purpose of this study is to determine the safety and maximum tolerated dose of GRN163L in
treating patients with refractory or relapsed chronic lymphoproliferative disease.
Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer
Completed
Geron Corporation
Phase 2
2010-11-01
The purpose of this study is to evaluate the efficacy and safety of treatment with imetelstat
+ paclitaxel (with or without bevacizumab) versus paclitaxel (with or without bevacizumab)
alone for patients with locally recurrent or metastatic breast cancer who have not received
chemotherapy or have received one non-taxane based chemotherapy for metastatic breast cancer.
A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
Completed
Breast Cancer Research Foundation
Phase 1
2011-01-01
A study to evaluate safety and biologic effects of giving GRN163L in combination with
trastuzumab in patients diagnosed with HER2+ metastatic breast cancer that is resistant to
therapy with trastuzumab.
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