TRAUMA HELP: Healing and Analgesia With Propranolol
Withdrawn
University of North Carolina, Chapel Hill
Phase 2
2009-10-01
The purpose of this study is to determine whether propranolol can decrease pain symptoms in a
common subset of patients admitted to a trauma center after injury.
Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
Completed
Stanford University
Phase 2
2009-02-01
This research study explores whether a beta-blocker (propranolol) can prevent a person from
becoming more sensitive to pain after administration of an opioid (remifentanil). Beta
blockers inhibit the sympathetic (fight or flight) response and are often used to treat
angina and high blood pressure. In a previous study in human volunteers, the investigators
demonstrated an increased sensitivity to pain after a 60-minute infusion of the opioid
remifentanil. The goal of this study is to identify a possible inhibitor of this phenomenon.
Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response
Completed
United States Department of Defense
Early Phase 1
2016-08-01
The purpose of this study is to find out how the brain of people with autism is affected by
Propranolol. Propranolol is not FDA approved for the treatment of autism. Propranolol is FDA
approved for the treatment of heart conditions such as blood pressure
This research is being done because there are currently no drug treatment options for
language impairments and social difficulties often experienced by people with autism.
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