Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Active, not recruiting
Institute for Neurodegenerative Disorders
Phase 2
2010-06-01
This is a observational, multi-center study to assess progression of clinical features,
imaging and biologic biomarkers in Parkinson disease (PD) patients compared to healthy
controls (HC) and in PD patient subtypes.
The primary objective of this study is to identify clinical, imaging and biologic markers of
PD progression for use in clinical trials of disease-modifying therapies.
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
Active, not recruiting
Ken Marek, MD
Phase 2
2010-06-01
This is a observational, multi-center study to assess progression of clinical features,
imaging and biologic biomarkers in Parkinson disease (PD) patients compared to healthy
controls (HC) and in PD patient subtypes.
The primary objective of this study is to identify clinical, imaging and biologic markers of
PD progression for use in clinical trials of disease-modifying therapies.
DaTSCAN Imaging in Aging and Neurodegenerative Disease
Enrolling by invitation
Mayo Clinic
Phase 4
2011-10-01
The investigators propose using DaTscan in patients with REM sleep behavior disorder (RBD),
mild cognitive impairment (MCI), Parkinson's disease (PD), dementia with Lewy bodies (DLB),
Alzheimer's disease (AD), and other neurodegenerative syndromes and disorders, to test
several hypotheses - some confirmatory, and some novel. Such use will provide new data on the
potential clinical and research utility of DaTscan in neurodegenerative diseases. The
findings on DaTscan will be correlated with clinical diagnoses and other multimodal imaging
studies (e.g., MRI, MRS, FDG-PET, and amyloid-PET) to enhance our understanding of
neurodegenerative diseases.
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