COmbined N-acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of contrasT
Completed
National University Hospital, Singapore
Phase 2/Phase 3
2007-08-01
This is a randomised controlled trial to investigate the efficacy of preventive regimen of
hydration with high dose oral N-acetylcysteine and intravenous sodium bicarbonate
pretreatment in patients with stable advanced renal insufficiency (CKD stage 3 and 4:GFR
15-60ml/min/1.73m2 calculated by Modification of Diet in Renal Disease Study equation (MDRD
formula)) undergoing elective percutaneous coronary intervention (PCI).
Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography
Terminated
Guerbet
Phase 4
2009-01-01
The purpose of this study is to evaluate the contrast-induced nephropathy (CIN) rate in
subjects randomized to receive either Ioversol or Iodixanol for contrast-enhanced computed
tomography.
Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography
Terminated
Mallinckrodt
Phase 4
2009-01-01
The purpose of this study is to evaluate the contrast-induced nephropathy (CIN) rate in
subjects randomized to receive either Ioversol or Iodixanol for contrast-enhanced computed
tomography.
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