CLINICAL TRIALS PROFILE FOR METROGEL

All Clinical Trials for metrogel

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00249782 ↗	A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea.	Completed	Allergan	Phase 2	2005-11-01	The purpose of this study is to evaluate the safety and effectiveness of ACZONE™ gel compared to placebo (inactive substance), MetroGel® and a combination of ACZONE™ gel and MetroGel® for the treatment of rosacea. ACZONE™ gel, 5% is a topical (applied to the skin) medication that is approved by the United States Food and Drug Administration (FDA) for the treatment of acne vulgaris in people 12 years and older. The use of ACZONE™ for the treatment of rosacea is investigational. An investigational use is one that is not approved by the FDA. Subjects will apply the study treatment for 12 weeks. Efficacy assessments will be performed at baseline and Weeks 2, 4, 8, and 12. Laboratory assessments will be conducted at baseline and Week, 2, 4 and 12.
NCT00436527 ↗	Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application	Completed	Galderma Laboratories, L.P.	Phase 4	2006-08-01	This eight-hour kinetic regression clinical study was conducted to assess the ability of MetroGel® 1% to deliver moisture to facial skin after a single application.
NCT00635622 ↗	Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial Vaginosis	Completed	University of California, San Francisco	Phase 2	2008-04-01	This is a phase IIa clinical trial in women with bacterial vaginosis. This study will determine whether treatment with vaginal lactobacillus in combination with antibiotic therapy (metronidazole) is effective in colonizing the vagina with the lactobacillus bacteria found in normal vaginal flora.
NCT00635622 ↗	Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial Vaginosis	Completed	Osel, Inc.	Phase 2	2008-04-01	This is a phase IIa clinical trial in women with bacterial vaginosis. This study will determine whether treatment with vaginal lactobacillus in combination with antibiotic therapy (metronidazole) is effective in colonizing the vagina with the lactobacillus bacteria found in normal vaginal flora.
NCT00668655 ↗	An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1%	Completed	Galderma Laboratories, L.P.		2008-02-01	The purpose of this study is to determine the cosmetic appearance of metronidazole gel (MetroGel®) 1% with commonly marketed facial foundations.
NCT01020396 ↗	Bioequivalence of Metronidazole Gel, 0.75% in the Treatment of Bacterial Vaginosis	Completed	Teva Pharmaceuticals USA	Phase 1/Phase 2	2002-01-01	The purpose of this study was to demonstrate comparable efficacy, safety, and tolerability of Teva Pharmaceuticals USA's generic formulation of Metronidazole Vaginal Gel, 0.75% and 3M Pharmaceuticals' MetroGel-Vaginal® metronidazole vaginal gel, 0.75% to establish clinical equivalence in the treatment of bacterial vaginosis.

Clinical Trial Conditions for metrogel

Condition Name

Condition Name for metrogel
Intervention	Trials
Rosacea	4
Bacterial Vaginosis	4
Skin Manifestations	2
Erythematotelangiectatic Rosacea	1

Condition MeSH

Condition MeSH for metrogel
Intervention	Trials
Rosacea	5
Vaginosis, Bacterial	5
Vaginal Diseases	5
Skin Manifestations	2

Clinical Trial Locations for metrogel

Trials by Country

Trials by Country for metrogel
Location	Trials
United States	69

Trials by US State

Trials by US State for metrogel
Location	Trials
California	6
Pennsylvania	6
New York	4
North Carolina	4
Florida	4

Clinical Trial Progress for metrogel

Clinical Trial Phase

Clinical Trial Phase for metrogel
Clinical Trial Phase	Trials
Phase 4	5
Phase 3	1
Phase 2	4

Clinical Trial Status

Clinical Trial Status for metrogel
Clinical Trial Phase	Trials
Completed	11
Terminated	2
Recruiting	1

Clinical Trial Sponsors for metrogel

Sponsor Name

Sponsor Name for metrogel
Sponsor	Trials
Galderma Laboratories, L.P.	5
Teva Pharmaceuticals USA	2
National Institute of Allergy and Infectious Diseases (NIAID)	1

Sponsor Type

Sponsor Type for metrogel
Sponsor	Trials
Industry	14
Other	2
NIH	1