CLINICAL TRIALS PROFILE FOR METYRAPONE
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505(b)(2) Clinical Trials for metyrapone
| Trial Type | Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|---|
| New Formulation | NCT03404817 ↗ | Single Dose Crossover Comparative Bioavailability and Food Effect Study of Two EMB-001 Formulations | Completed | National Institute on Drug Abuse (NIDA) | Phase 1 | 2018-03-01 | This is a study of EMB-001 (a combination of two FDA-approved drugs, metyrapone and oxazepam) in healthy adults.This is a Phase 1, single dose, 3-period, 3-sequence, crossover study in 9 healthy male and female (not of childbearing potential) volunteers. The study will evaluate the bioavailability and food effect of a new formulation of EMB-001 relative to the original formulation of EMB 001. During the study, a total of 9 eligible subjects will be randomized in a 1:1:1 ratio to each of 3 treatment sequences |
| New Formulation | NCT03404817 ↗ | Single Dose Crossover Comparative Bioavailability and Food Effect Study of Two EMB-001 Formulations | Completed | Embera NeuroTherapeutics, Inc. | Phase 1 | 2018-03-01 | This is a study of EMB-001 (a combination of two FDA-approved drugs, metyrapone and oxazepam) in healthy adults.This is a Phase 1, single dose, 3-period, 3-sequence, crossover study in 9 healthy male and female (not of childbearing potential) volunteers. The study will evaluate the bioavailability and food effect of a new formulation of EMB-001 relative to the original formulation of EMB 001. During the study, a total of 9 eligible subjects will be randomized in a 1:1:1 ratio to each of 3 treatment sequences |
| >Trial Type | >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
All Clinical Trials for metyrapone
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00006270 ↗ | Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury | Unknown status | University of Texas | 1998-02-01 | OBJECTIVES: I. Determine the randomness of adrenocorticotropic hormone (ACTH) and cortisol secretion using approximate entropy in patients who have sustained a head injury. II. Determine the correlation between randomness of ACTH and cortisol secretion and stages of sleep in these patients. | |
| NCT00006270 ↗ | Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury | Unknown status | National Center for Research Resources (NCRR) | 1998-02-01 | OBJECTIVES: I. Determine the randomness of adrenocorticotropic hormone (ACTH) and cortisol secretion using approximate entropy in patients who have sustained a head injury. II. Determine the correlation between randomness of ACTH and cortisol secretion and stages of sleep in these patients. | |
| NCT00033098 ↗ | Cocaine-Metyrapone Interaction Study - 1 | Unknown status | Cincinnati VA Medical Center | Phase 1 | 2001-11-01 | The purpose of this study is to examine the safety of two consecutive days of metyrapone (MRP) in subjects who may use cocaine concurrently. |
| NCT00033098 ↗ | Cocaine-Metyrapone Interaction Study - 1 | Unknown status | National Institute on Drug Abuse (NIDA) | Phase 1 | 2001-11-01 | The purpose of this study is to examine the safety of two consecutive days of metyrapone (MRP) in subjects who may use cocaine concurrently. |
| NCT00125554 ↗ | Metyrapone as Additive Treatment in Major Depression | Completed | Universitätsklinikum Hamburg-Eppendorf | Phase 2 | 1998-05-01 | The purpose of this study is to test whether metyrapone is an effective and safe augmenting agent in the treatment of major depression. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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