CLINICAL TRIALS PROFILE FOR MILRINONE LACTATE

All Clinical Trials for milrinone lactate

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00446017 ↗	The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG	Completed	Deutsche Stiftung für Herzforschung	Phase 3	2003-06-01	Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support after coronary-artery-bypass-grafting. With respect to data derived from patients with sepsis shock and results from studies using phosphodiesterase-inhibitors prophylactically, the hypothesis is tested that adrenaline may be associated with unwarranted metabolic effects (hyperlactatemia and hyperglycemia) and renal dysfunction.
NCT00446017 ↗	The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG	Completed	University of Luebeck	Phase 3	2003-06-01	Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support after coronary-artery-bypass-grafting. With respect to data derived from patients with sepsis shock and results from studies using phosphodiesterase-inhibitors prophylactically, the hypothesis is tested that adrenaline may be associated with unwarranted metabolic effects (hyperlactatemia and hyperglycemia) and renal dysfunction.
NCT00695929 ↗	Levosimendan in Congenital Cardiac Surgery	Completed	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	N/A	2008-07-01	Many pediatric patients undergoing cardiac surgery under cardiopulmonary bypass for repair of complex congenital malformations, require inotropic support for low cardiac output syndrome. Milrinone through its positive inotropic and vasodilatory effects is widely used for this purpose. The aim of the study is to compare Milrinone with Levosimendan, a novel inotope with calcium-sensitizing properties. We hypothesized that using Levosimendan would result in reduced serum lactate through a higher cardiac index.
NCT01088997 ↗	Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn	Terminated	American Medical Association	N/A	2010-06-01	The purpose of this pilot study is to determine a safe dose of milrinone to use in a larger study of babies with persistent pulmonary hypertension of the newborn (PPHN).
NCT01088997 ↗	Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn	Terminated	Bedford Pharmaceuticals	N/A	2010-06-01	The purpose of this pilot study is to determine a safe dose of milrinone to use in a larger study of babies with persistent pulmonary hypertension of the newborn (PPHN).
NCT01088997 ↗	Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn	Terminated	Thrasher Research Fund	N/A	2010-06-01	The purpose of this pilot study is to determine a safe dose of milrinone to use in a larger study of babies with persistent pulmonary hypertension of the newborn (PPHN).
NCT01088997 ↗	Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn	Terminated	University of Pennsylvania	N/A	2010-06-01	The purpose of this pilot study is to determine a safe dose of milrinone to use in a larger study of babies with persistent pulmonary hypertension of the newborn (PPHN).

Clinical Trial Conditions for milrinone lactate

Condition Name

Condition Name for milrinone lactate
Intervention	Trials
Low Cardiac Output Syndrome	3
Cardiac Output, Low	1
Cardiac Surgical Procedures	1
Cardiogenic Shock	1

Condition MeSH

Condition MeSH for milrinone lactate
Intervention	Trials
Cardiac Output, Low	4
Syndrome	2
Critical Illness	1
Acute Coronary Syndrome	1

Clinical Trial Locations for milrinone lactate

Trials by Country

Trials by Country for milrinone lactate
Location	Trials
United States	2
Canada	1
Belgium	1
China	1

Trials by US State

Trials by US State for milrinone lactate
Location	Trials
Pennsylvania	1
Michigan	1

Clinical Trial Progress for milrinone lactate

Clinical Trial Phase

Clinical Trial Phase for milrinone lactate
Clinical Trial Phase	Trials
Phase 4	1
Phase 3	2
N/A	2

Clinical Trial Status

Clinical Trial Status for milrinone lactate
Clinical Trial Phase	Trials
Completed	3
Terminated	1
Unknown status	1

Clinical Trial Sponsors for milrinone lactate

Sponsor Name

Sponsor Name for milrinone lactate
Sponsor	Trials
University of Luebeck	1
Cliniques universitaires Saint-Luc- Université Catholique de Louvain	1
American Medical Association	1

Sponsor Type

Sponsor Type for milrinone lactate
Sponsor	Trials
Other	9
Industry	1