Dose-finding Study for the Ultralow-dose Levonorgestrel Intrauterine Contraceptive System (LCS)
Completed
Bayer
Phase 2
2005-04-01
The purpose of this study is to investigate if drug doses lower than the one released from
Mirena® would be as effective for contraception as Mirena®. Subjects participating in the
study will be randomly assigned to be inserted with any of the three different intrauterine
systems (IUSs). The IUSs are nearly alike except that the amount of hormone released from
them is different.
Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)
Completed
Bayer
Phase 3
2006-07-01
The purpose of this study is to determine whether the levonorgestrel-releasing intrauterine
system is effective in decreasing menstrual blood loss.
Bleeding Pattern and User Satisfaction During Second Consecutive MIRENA® in Contraception and Treatment of Menorrhagia
Completed
Bayer
Phase 4
2006-10-01
The purpose of this study is to assess the bleeding pattern during the last 3 months of the
first MIRENA® and the first year of the second MIRENA® use.
Levonorgestrel in Preventing Ovarian Cancer in Patients at High Risk for Ovarian Cancer
Completed
National Cancer Institute (NCI)
Phase 2
2008-03-10
This randomized phase II trial is studying how well levonorgestrel works in preventing
ovarian cancer in patients at high risk for ovarian cancer. Chemoprevention is the use of
certain drugs to keep cancer from forming. The use of levonorgestrel may prevent ovarian
cancer.
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