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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR NOXAFIL


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All Clinical Trials for noxafil

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00491764 ↗ A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED) Completed Merck Sharp & Dohme Corp. Phase 2 2007-06-01 The purpose of this study is to evaluate the efficacy, safety, and tolerability of oral administration of four dosing regimens of posaconazole relative to placebo and terbinafine, in the treatment of toenail onychomycosis.
NCT00726609 ↗ Post-marketing Surveillance Study of Invasive Mycosis With Posaconazole (Study P04641) Completed Merck Sharp & Dohme Corp. 2006-01-01 The purpose of this postmarketing surveillance study is to collect an extensive body of data in a large patient population in every day life to investigate the safety and efficacy of NOXAFIL® (posaconazole) in the treatment of invasive fungal disease.
NCT00750737 ↗ Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC) Completed Enzon Pharmaceuticals, Inc. Phase 3 2008-06-01 The objective of this study is to compare the safety and efficacy of ABLC versus oral Posaconazole in the prevention of invasive fungal infections in high risk patients with hematologic malignancies or hematopoietic stem cell transplant. Primary objective is to demonstrate the low toxicity rate and low rate of invasive fungal infections associated with ABLC or Posaconazole prophylaxis. Secondary objective will be to compare the cost effectiveness of these two prophylactic regimens.
NCT00750737 ↗ Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC) Completed M.D. Anderson Cancer Center Phase 3 2008-06-01 The objective of this study is to compare the safety and efficacy of ABLC versus oral Posaconazole in the prevention of invasive fungal infections in high risk patients with hematologic malignancies or hematopoietic stem cell transplant. Primary objective is to demonstrate the low toxicity rate and low rate of invasive fungal infections associated with ABLC or Posaconazole prophylaxis. Secondary objective will be to compare the cost effectiveness of these two prophylactic regimens.
NCT00799071 ↗ Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) Completed Radboud University Phase 2 2009-02-01 The purpose of this study is to find a dose for a twice daily regimen for posaconazole (PSZ) as prophylactic treatment in children with CGD, based on the PSZ trough level.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for noxafil

Condition Name

Condition Name for noxafil
Intervention Trials
Fungal Infection 6
Mycoses 3
Fungal Infections 2
Leukemia, Myeloid, Acute 2
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Condition MeSH

Condition MeSH for noxafil
Intervention Trials
Mycoses 14
Invasive Fungal Infections 7
Leukemia 5
Infections 5
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Clinical Trial Locations for noxafil

Trials by Country

Trials by Country for noxafil
Location Trials
United States 11
Belgium 7
Netherlands 7
China 3
Spain 2
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Trials by US State

Trials by US State for noxafil
Location Trials
Texas 3
Pennsylvania 2
Missouri 2
North Carolina 1
New York 1
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Clinical Trial Progress for noxafil

Clinical Trial Phase

Clinical Trial Phase for noxafil
Clinical Trial Phase Trials
Phase 4 4
Phase 3 4
Phase 2 3
[disabled in preview] 6
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Clinical Trial Status

Clinical Trial Status for noxafil
Clinical Trial Phase Trials
Completed 16
Recruiting 4
Terminated 1
[disabled in preview] 2
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Clinical Trial Sponsors for noxafil

Sponsor Name

Sponsor Name for noxafil
Sponsor Trials
Merck Sharp & Dohme Corp. 9
Radboud University 4
M.D. Anderson Cancer Center 3
[disabled in preview] 3
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Sponsor Type

Sponsor Type for noxafil
Sponsor Trials
Other 20
Industry 14
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