Nexium Study To Suppress Nausea During Chemotherapy
Terminated
AstraZeneca
Phase 3
2005-08-01
This study will look at a drug called esomeprazole, the newest PPI, as a way to further
reduce the amount of nausea and vomiting seen in breast cancer patients receiving adriamycin
or epirubicin chemotherapy. Esomeprazole may help protect the gut lining from the stomach
acid and thus lessen the nausea and vomiting. If patients have less stomach sickness, they
may be able to enjoy their daily routines much more while they are getting chemotherapy.
Nexium Study To Suppress Nausea During Chemotherapy
Terminated
Baylor Breast Care Center
Phase 3
2005-08-01
This study will look at a drug called esomeprazole, the newest PPI, as a way to further
reduce the amount of nausea and vomiting seen in breast cancer patients receiving adriamycin
or epirubicin chemotherapy. Esomeprazole may help protect the gut lining from the stomach
acid and thus lessen the nausea and vomiting. If patients have less stomach sickness, they
may be able to enjoy their daily routines much more while they are getting chemotherapy.
A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (CL2007-17 )(P07813)(COMPLETED)
Completed
Bausch Health Americas, Inc.
Phase 3
2008-04-01
Open-label randomized crossover design studies. 60 participants will be evaluated on Day 1 to
compare effects on stomach acid; 30 participants will continue treatment for 7 days and will
have repeat evaluations at Day 7. The other 30 participants will receive a single
administration of sodium bicarbonate.
A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (CL2007-17 )(P07813)(COMPLETED)
Completed
Valeant Pharmaceuticals International, Inc.
Phase 3
2008-04-01
Open-label randomized crossover design studies. 60 participants will be evaluated on Day 1 to
compare effects on stomach acid; 30 participants will continue treatment for 7 days and will
have repeat evaluations at Day 7. The other 30 participants will receive a single
administration of sodium bicarbonate.
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