Preemptive Analgesia With OxyContin Versus Placebo Before Surgery for Long Bone Fractures
Completed
Rambam Health Care Campus
Phase 4
2007-04-01
We would like to check whether pre-operative administration of an oral controlled-release
opioid formulation (Oxycodone hydrochloride (OxyContin)) could result in a clear effect of
preemptive analgesia.
An Effectiveness, Safety and Quality of Life Measures With Hydromorphone HCL, Dilaudid CR (Controlled Release)
Completed
Alza Corporation, DE, USA
Phase 3
1969-12-31
The purpose of this study was to characterize the effectiveness and safety of OROS
hydromorphone HCL and OxyContin in patients with chronic osteoarthritis (OA) of the knee or
hip who are receiving chronic nonsteroidal anti-inflammatory drug (NSAID) or other
nonsteroidal, non-opioid analgesic (ie, acetaminophen or aspirin) therapy.
Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
Terminated
Endo Pharmaceuticals
Phase 4
2007-01-01
This study will determine whether treatment with an extended-release opioid or topical
lidocaine is effective in relieving distal symmetric lower extremity burning pain associated
with multiple sclerosis (MS). If treatment with topical lidocaine is efficacious, it will
have important implications for understanding this chronic pain syndrome, which is widely
assumed to be caused by central nervous system pathology.
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