Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation.
Completed
Helsinn Healthcare SA
Phase 2
2006-03-01
The primary purpose of this study is to explore the efficacy of three different dose
schedules of palonosetron for the prevention of emesis over a 7-day study interval in
multiple myeloma patients.
Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation.
Completed
Eisai Inc.
Phase 2
2006-03-01
The primary purpose of this study is to explore the efficacy of three different dose
schedules of palonosetron for the prevention of emesis over a 7-day study interval in
multiple myeloma patients.
APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
Completed
Heron Therapeutics
Phase 3
2006-06-01
This randomized phase III trial is studying APF530 and dexamethasone to see how well they
work compared with palonosetron and dexamethasone in preventing nausea and vomiting in
patients receiving chemotherapy for cancer.
Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer
Completed
National Cancer Institute (NCI)
N/A
2006-01-01
RATIONALE: Antiemetic drugs, such as dexamethasone, ondansetron hydrochloride, and
palonosetron hydrochloride, may help lessen or prevent nausea and vomiting caused by
chemotherapy.
PURPOSE: This clinical trial studies how well giving dexamethasone together with ondansetron
hydrochloride or palonosetron hydrochloride works in preventing nausea and vomiting in
patients receiving doxorubicin hydrochloride and cyclophosphamide for early stage breast
cancer
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