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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR PALONOSETRON HYDROCHLORIDE


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All Clinical Trials for palonosetron hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00306735 ↗ Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation. Completed Helsinn Healthcare SA Phase 2 2006-03-01 The primary purpose of this study is to explore the efficacy of three different dose schedules of palonosetron for the prevention of emesis over a 7-day study interval in multiple myeloma patients.
NCT00306735 ↗ Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation. Completed Eisai Inc. Phase 2 2006-03-01 The primary purpose of this study is to explore the efficacy of three different dose schedules of palonosetron for the prevention of emesis over a 7-day study interval in multiple myeloma patients.
NCT00343460 ↗ APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer Completed Heron Therapeutics Phase 3 2006-06-01 This randomized phase III trial is studying APF530 and dexamethasone to see how well they work compared with palonosetron and dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for cancer.
NCT00343863 ↗ Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer Completed National Cancer Institute (NCI) N/A 2006-01-01 RATIONALE: Antiemetic drugs, such as dexamethasone, ondansetron hydrochloride, and palonosetron hydrochloride, may help lessen or prevent nausea and vomiting caused by chemotherapy. PURPOSE: This clinical trial studies how well giving dexamethasone together with ondansetron hydrochloride or palonosetron hydrochloride works in preventing nausea and vomiting in patients receiving doxorubicin hydrochloride and cyclophosphamide for early stage breast cancer
NCT00343863 ↗ Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer Completed University of Washington N/A 2006-01-01 RATIONALE: Antiemetic drugs, such as dexamethasone, ondansetron hydrochloride, and palonosetron hydrochloride, may help lessen or prevent nausea and vomiting caused by chemotherapy. PURPOSE: This clinical trial studies how well giving dexamethasone together with ondansetron hydrochloride or palonosetron hydrochloride works in preventing nausea and vomiting in patients receiving doxorubicin hydrochloride and cyclophosphamide for early stage breast cancer
NCT00359567 ↗ Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic Chemotherapy Completed Taiho Pharmaceutical Co., Ltd. Phase 3 2006-07-01 To compare palonosetron with granisetron hydrochloride as a control in the efficacy of intravenous single dose in preventing acute and delayed gastro-intestinal disorders, such as nausea and vomiting induced by highly emetogenic chemotherapy.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for palonosetron hydrochloride

Condition Name

Condition Name for palonosetron hydrochloride
Intervention Trials
Chemotherapy-Induced Nausea and Vomiting 31
Postoperative Nausea and Vomiting 17
Nausea 14
Vomiting 13
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Condition MeSH

Condition MeSH for palonosetron hydrochloride
Intervention Trials
Vomiting 95
Nausea 79
Postoperative Nausea and Vomiting 24
Breast Neoplasms 7
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Clinical Trial Locations for palonosetron hydrochloride

Trials by Country

Trials by Country for palonosetron hydrochloride
Location Trials
United States 280
China 29
Italy 22
Korea, Republic of 17
Russian Federation 9
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Trials by US State

Trials by US State for palonosetron hydrochloride
Location Trials
Texas 15
Ohio 15
Florida 13
New York 13
South Carolina 13
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Clinical Trial Progress for palonosetron hydrochloride

Clinical Trial Phase

Clinical Trial Phase for palonosetron hydrochloride
Clinical Trial Phase Trials
Phase 4 21
Phase 3 34
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for palonosetron hydrochloride
Clinical Trial Phase Trials
Completed 72
Unknown status 15
Recruiting 13
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Clinical Trial Sponsors for palonosetron hydrochloride

Sponsor Name

Sponsor Name for palonosetron hydrochloride
Sponsor Trials
Helsinn Healthcare SA 15
National Cancer Institute (NCI) 11
Eisai Inc. 11
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Sponsor Type

Sponsor Type for palonosetron hydrochloride
Sponsor Trials
Other 145
Industry 59
NIH 14
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