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Last Updated: November 4, 2024

CLINICAL TRIALS PROFILE FOR PERFLUBRON


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All Clinical Trials for perflubron

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02616770 ↗ Phase1, Placebo-Controlled, Randomized, Double-blind, Single-ascending Dose Study in Healthy Subjects. Completed SolAeroMed Inc. Phase 1 2014-03-01 To evaluate the safety and tolerability of S-1226 composed of perflubron with ascending doses of carbon dioxide (4%, 8%, and 12% CO2) administered over 2 minute nebulisation to healthy subjects.
NCT03041740 ↗ Fluid Filled Lung Oxygenation Assistance Trial Active, not recruiting ADAGP Charitable Foundation dba Auto Dealers CARing for Kids Foundation Phase 1 2017-06-27 The primary study objective is to assess the safety and feasibility of perfluorooctylbromide (PFOB) partial liquid ventilation (PLV) in infants with severe Bronchopulmonary Dysplasia (BPD).
NCT03041740 ↗ Fluid Filled Lung Oxygenation Assistance Trial Active, not recruiting Auto Dealers Caring for Kids Foundation Phase 1 2017-06-27 The primary study objective is to assess the safety and feasibility of perfluorooctylbromide (PFOB) partial liquid ventilation (PLV) in infants with severe Bronchopulmonary Dysplasia (BPD).
NCT03041740 ↗ Fluid Filled Lung Oxygenation Assistance Trial Active, not recruiting Children's Hospital of Philadelphia Phase 1 2017-06-27 The primary study objective is to assess the safety and feasibility of perfluorooctylbromide (PFOB) partial liquid ventilation (PLV) in infants with severe Bronchopulmonary Dysplasia (BPD).
NCT04738136 ↗ Safety, Tolerability and Efficacy Of S-1226 in Moderate Severity Covid-19 Bronchiolitis/Pneumonia Suspended SolAeroMed Inc. Phase 2 2021-09-15 This is a randomized, open-label, controlled, Phase II proof of concept study to evaluate the safety, tolerability and efficacy of S-1226 in which hospitalized subjects (n≤30) with moderate severity COVID-19 Bronchiolitis/Pneumonia will be enrolled. The safety and tolerability of S-1226 composed of PFOB with ascending doses of carbon dioxide (4%, 8%, and 12% CO2) administered twice daily will be assessed subjects in hospitalized subjects with moderate severity COVID-19 Bronchiolitis/Pneumonia.
NCT04949386 ↗ Safety, Tolerability and Efficacy of S-1226 in Post-COVID-19 Subjects With Persistent Respiratory Symptoms. Not yet recruiting SolAeroMed Inc. Phase 2 2021-09-01 This is a randomized (1:1) , placebo-controlled phase II study to evaluate the safety, tolerability and efficacy of S-1226 in Post-COVID-19 subjects (n≤48) with persistent respiratory symptoms. Subjects will receive twice daily treatments of either Placebo or S-1226 (8%) for 7 days.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for perflubron

Condition Name

Condition Name for perflubron
Intervention Trials
Asthma 1
Bronchopulmonary Dysplasia 1
COVID-19 Respiratory Infection 1
Covid19 1
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Condition MeSH

Condition MeSH for perflubron
Intervention Trials
COVID-19 2
Bronchiolitis 1
Bronchopulmonary Dysplasia 1
Signs and Symptoms, Respiratory 1
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Clinical Trial Locations for perflubron

Trials by Country

Trials by Country for perflubron
Location Trials
Canada 1
United States 1
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Trials by US State

Trials by US State for perflubron
Location Trials
Pennsylvania 1
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Clinical Trial Progress for perflubron

Clinical Trial Phase

Clinical Trial Phase for perflubron
Clinical Trial Phase Trials
Phase 2 2
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for perflubron
Clinical Trial Phase Trials
Active, not recruiting 1
Completed 1
Not yet recruiting 1
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Clinical Trial Sponsors for perflubron

Sponsor Name

Sponsor Name for perflubron
Sponsor Trials
SolAeroMed Inc. 3
ADAGP Charitable Foundation dba Auto Dealers CARing for Kids Foundation 1
Auto Dealers Caring for Kids Foundation 1
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Sponsor Type

Sponsor Type for perflubron
Sponsor Trials
Industry 3
Other 3
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