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Last Updated: November 23, 2024

CLINICAL TRIALS PROFILE FOR PEXIDARTINIB HYDROCHLORIDE


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All Clinical Trials for pexidartinib hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01349036 ↗ A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma Terminated Plexxikon Phase 2 2011-12-03 The objective of this study is to evaluate the response of subjects with recurrent glioblastoma to continuous therapy of PLX3397.
NCT01349036 ↗ A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma Terminated Daiichi Sankyo, Inc. Phase 2 2011-12-03 The objective of this study is to evaluate the response of subjects with recurrent glioblastoma to continuous therapy of PLX3397.
NCT01525602 ↗ Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors Completed Plexxikon Phase 1 2012-05-01 This was a 3-part study designed to explore the safety and tolerability of escalating doses of PLX3397 with weekly paclitaxel to establish a recommended Phase 2 dose (RP2D), to confirm RP2D in participants with advanced non-resectable solid tumors, and to determine the efficacy of PLX3397 600 mg twice daily (BID) administered in combination with weekly paclitaxel in participants with advanced, metastatic or non-resectable, platinum-resistant or -refractory epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer.
NCT01525602 ↗ Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors Completed Daiichi Sankyo, Inc. Phase 1 2012-05-01 This was a 3-part study designed to explore the safety and tolerability of escalating doses of PLX3397 with weekly paclitaxel to establish a recommended Phase 2 dose (RP2D), to confirm RP2D in participants with advanced non-resectable solid tumors, and to determine the efficacy of PLX3397 600 mg twice daily (BID) administered in combination with weekly paclitaxel in participants with advanced, metastatic or non-resectable, platinum-resistant or -refractory epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for pexidartinib hydrochloride

Condition Name

Condition Name for pexidartinib hydrochloride
Intervention Trials
Tenosynovial Giant Cell Tumor 4
Melanoma 2
Gastrointestinal Stromal Tumor (GIST) 2
Giant Cell Tumors of the Tendon Sheath 1
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Condition MeSH

Condition MeSH for pexidartinib hydrochloride
Intervention Trials
Giant Cell Tumors 4
Giant Cell Tumor of Tendon Sheath 4
Neoplasms 3
Gastrointestinal Stromal Tumors 3
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Clinical Trial Locations for pexidartinib hydrochloride

Trials by Country

Trials by Country for pexidartinib hydrochloride
Location Trials
United States 68
Korea, Republic of 6
Australia 5
Taiwan 4
Netherlands 3
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Trials by US State

Trials by US State for pexidartinib hydrochloride
Location Trials
New York 8
Massachusetts 7
California 7
Texas 6
Michigan 5
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Clinical Trial Progress for pexidartinib hydrochloride

Clinical Trial Phase

Clinical Trial Phase for pexidartinib hydrochloride
Clinical Trial Phase Trials
Phase 4 1
Phase 3 2
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for pexidartinib hydrochloride
Clinical Trial Phase Trials
Completed 11
Recruiting 2
Terminated 2
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Clinical Trial Sponsors for pexidartinib hydrochloride

Sponsor Name

Sponsor Name for pexidartinib hydrochloride
Sponsor Trials
Plexxikon 13
Daiichi Sankyo, Inc. 11
Daiichi Sankyo Co., Ltd. 4
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Sponsor Type

Sponsor Type for pexidartinib hydrochloride
Sponsor Trials
Industry 35
Other 2
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