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Last Updated: November 25, 2024

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CLINICAL TRIALS PROFILE FOR PREVYMIS


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All Clinical Trials for prevymis

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03728426 ↗ Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection Recruiting Merck Sharp & Dohme Corp. Phase 2 2019-01-11 The trial will evaluate the safety and efficacy of letermovir antiviral treatment of active cytomegalovirus infection or cytomegalovirus disease in patients with infections that are refractory or resistant to available treatments or who are experiencing organ dysfunction that makes unsafe the use of available antiviral treatments.
NCT03728426 ↗ Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection Recruiting Amy C. Sherman, MD Phase 2 2019-01-11 The trial will evaluate the safety and efficacy of letermovir antiviral treatment of active cytomegalovirus infection or cytomegalovirus disease in patients with infections that are refractory or resistant to available treatments or who are experiencing organ dysfunction that makes unsafe the use of available antiviral treatments.
NCT03728426 ↗ Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection Recruiting Dana-Farber Cancer Institute Phase 2 2019-01-11 The trial will evaluate the safety and efficacy of letermovir antiviral treatment of active cytomegalovirus infection or cytomegalovirus disease in patients with infections that are refractory or resistant to available treatments or who are experiencing organ dysfunction that makes unsafe the use of available antiviral treatments.
NCT04060277 ↗ Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation Recruiting National Cancer Institute (NCI) Phase 2 2019-10-07 This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may be carried for life and does not cause illness in most healthy individuals. However, in people whose immune systems are lowered (such as those undergoing stem cell transplantation), CMV can reproduce and cause disease and even death. The Triplex vaccine is made up of 3 small pieces of CMV deoxyribonucleic acid (DNA) (the chemical form of genes) placed into a weakened virus called modified vaccinia Ankara (MVA) that may help produce immunity (the ability to recognize and respond to an infection) and reduce the risk of developing complications related to CMV infection.
NCT04060277 ↗ Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation Recruiting City of Hope Medical Center Phase 2 2019-10-07 This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may be carried for life and does not cause illness in most healthy individuals. However, in people whose immune systems are lowered (such as those undergoing stem cell transplantation), CMV can reproduce and cause disease and even death. The Triplex vaccine is made up of 3 small pieces of CMV deoxyribonucleic acid (DNA) (the chemical form of genes) placed into a weakened virus called modified vaccinia Ankara (MVA) that may help produce immunity (the ability to recognize and respond to an infection) and reduce the risk of developing complications related to CMV infection.
NCT04312841 ↗ Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab Recruiting Merck Sharp & Dohme Corp. Phase 2 2020-09-15 This phase II trial studies how well letermovir works for the prevention of cytomegalovirus reactivation in patients with hematological malignancies treated with alemtuzumab. Patients receiving treatment with alemtuzumab may experience cytomegalovirus reactivation. Letermovir may block cytomegalovirus replication and prevent infection.
NCT04312841 ↗ Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab Recruiting National Cancer Institute (NCI) Phase 2 2020-09-15 This phase II trial studies how well letermovir works for the prevention of cytomegalovirus reactivation in patients with hematological malignancies treated with alemtuzumab. Patients receiving treatment with alemtuzumab may experience cytomegalovirus reactivation. Letermovir may block cytomegalovirus replication and prevent infection.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for prevymis

Condition Name

Condition Name for prevymis
Intervention Trials
Hematopoietic and Lymphoid Cell Neoplasm 2
Chronic Lymphocytic Leukemia 2
Cytomegalovirus Infections 1
Myelofibrosis 1
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Condition MeSH

Condition MeSH for prevymis
Intervention Trials
Lymphoma 2
Leukemia, Lymphocytic, Chronic, B-Cell 2
Neoplasms 2
Leukemia 2
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Clinical Trial Locations for prevymis

Trials by Country

Trials by Country for prevymis
Location Trials
United States 5
Canada 1
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Trials by US State

Trials by US State for prevymis
Location Trials
California 2
Massachusetts 1
Pennsylvania 1
Ohio 1
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Clinical Trial Progress for prevymis

Clinical Trial Phase

Clinical Trial Phase for prevymis
Clinical Trial Phase Trials
Phase 3 1
Phase 2 5
N/A 1
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Clinical Trial Status

Clinical Trial Status for prevymis
Clinical Trial Phase Trials
Not yet recruiting 4
Recruiting 3
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Clinical Trial Sponsors for prevymis

Sponsor Name

Sponsor Name for prevymis
Sponsor Trials
Merck Sharp & Dohme Corp. 4
National Cancer Institute (NCI) 2
Jean-Pierre Routy 1
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Sponsor Type

Sponsor Type for prevymis
Sponsor Trials
Other 7
Industry 4
NIH 3
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