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Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR RIOCIGUAT

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All Clinical Trials for riociguat

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00855660 ↗	Effect of Riociguat on Bone Metabolism	Completed	Bayer	Phase 1	2009-03-01	Investigation of the effect of Riociguat, administered as 2.5 mg IR-tablets TID over 14 days, on bone metabolism.
NCT01014247 ↗	Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation	Completed	Bayer	Phase 1	2009-11-01	The aim of this study is to investigate the effect of moxifloxacin on the QT interval in order to gain information on the validity of results that will be collected during another clinical study testing riociguat in patients with pulmonary arterial hypertension (PATENT-1 study).
NCT01065051 ↗	Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics	Terminated	Bayer	Phase 2	2010-11-01	The aim of this study is to assess whether oral Riociguat affects the left ventricular contractility and relaxation in patients with pulmonary hypertension associated with left ventricular systolic dysfunction
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for riociguat

Condition Name

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Condition Name for riociguat
Intervention	Trials
Hypertension, Pulmonary	13
Chronic Thromboembolic Pulmonary Hypertension	5
Pulmonary Arterial Hypertension	4
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Condition MeSH

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Condition MeSH for riociguat
Intervention	Trials
Hypertension	25
Hypertension, Pulmonary	24
Pulmonary Arterial Hypertension	10
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Clinical Trial Locations for riociguat

Trials by Country

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Trials by Country for riociguat
Location	Trials
United States	143
Germany	71
Japan	39
Italy	28
United Kingdom	26
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Trials by US State

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Trials by US State for riociguat
Location	Trials
Massachusetts	10
Pennsylvania	9
Ohio	9
New York	9
California	9
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Clinical Trial Progress for riociguat

Clinical Trial Phase

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Clinical Trial Phase for riociguat
Clinical Trial Phase	Trials
Phase 4	7
Phase 3	5
Phase 2/Phase 3	1
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Clinical Trial Status

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Clinical Trial Status for riociguat
Clinical Trial Phase	Trials
Completed	19
Recruiting	15
Not yet recruiting	5
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Clinical Trial Sponsors for riociguat

Sponsor Name

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Sponsor Name for riociguat
Sponsor	Trials
Bayer	27
Actelion	4
Merck Sharp & Dohme Corp.	4
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Sponsor Type

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Sponsor Type for riociguat
Sponsor	Trials
Industry	38
Other	28
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