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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR RIVASTIGMINE


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All Clinical Trials for rivastigmine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000174 ↗ Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx) Completed Novartis Phase 3 1969-12-31 This phase IIIb trial is a prospective, randomized, double-blind, placebo-controlled, 36-month study comparing the length of time of progression from mild cognitive impairment (MCI) to a clinical diagnosis of Alzheimer's disease (AD) in subjects taking Exelon vs. placebo. Exelon is currently under review with the U.S. Food and Drug Administration as a treatment for Alzheimer's disease. The drug has been cleared for marketing in more than 40 countries for Alzheimer's disease to date, including all 15 member states of the European Union, New Zealand, Argentina, Brazil and Mexico. Each subject with MCI will be randomly assigned to treatment with either Exelon or placebo. Subjects assigned to Exelon will receive 1.5 to 6.0 mg bid (twice daily) (3.0 to 12 mg/day) for the majority of the study. At every regular visit scheduled every three months, patients will be given basic efficacy and safety assessments. These assessments will include evaluation of adverse events, vital signs, activities of daily living, and clinical staging scales to determine if the subject may have converted to dementia.
NCT00099216 ↗ Efficacy and Safety of Rivastigmine Capsules in Patients With Probable Vascular Dementia Completed Novartis Pharmaceuticals Phase 3 2001-08-01 The goal of this research study is to evaluate the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable vascular dementia.
NCT00099242 ↗ Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease Completed Novartis Phase 3 2003-11-01 The goal of this research study is to evaluate the safety and efficacy of the rivastigmine transdermal patch in patients with probable Alzheimer's Disease.
NCT00099242 ↗ Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease Completed Novartis Pharmaceuticals Phase 3 2003-11-01 The goal of this research study is to evaluate the safety and efficacy of the rivastigmine transdermal patch in patients with probable Alzheimer's Disease.
NCT00102284 ↗ Neuromodulation and Language Acquisition (Project Stage Ia) Terminated University Hospital Muenster Phase 4 2004-03-01 The purpose of this study is to determine whether levodopa, pergolid, rivastigmine, or modafinil are effective in boosting semantic language acquisition in healthy subjects.
NCT00102856 ↗ Neuromodulation and Language Acquisition (Stage Ib) Suspended University Hospital Muenster Phase 4 2005-01-01 The purpose of this study is to determine whether rivastigmine or pramipexol are effective in boosting semantic language acquisition in healthy subjects.
NCT00104442 ↗ Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease Completed Novartis Phase 4 2003-10-01 Alzheimer's disease is a medical illness that damages the brain and causes problems with memory, mood and behavior. A substance called acetylcholine (ACh), which is naturally produced in the body, plays an important role in the normal functioning of the brain. In subjects with Alzheimer's disease, the level of ACh is greatly reduced. Currently, there are three commonly prescribed drugs used for treating the symptoms of Alzheimer's disease by helping to maintain the level of ACh in the brain. This study will evaluate how much each of these drugs changes the levels of certain brain chemicals that are known to, or may play an important role in, Alzheimer's disease and its symptoms.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for rivastigmine

Condition Name

Condition Name for rivastigmine
Intervention Trials
Alzheimer's Disease 32
Alzheimer Disease 13
Delirium 7
Healthy 5
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Condition MeSH

Condition MeSH for rivastigmine
Intervention Trials
Alzheimer Disease 52
Dementia 20
Cognition Disorders 11
Cognitive Dysfunction 11
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Clinical Trial Locations for rivastigmine

Trials by Country

Trials by Country for rivastigmine
Location Trials
United States 198
Japan 46
Canada 22
Italy 20
Germany 18
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Trials by US State

Trials by US State for rivastigmine
Location Trials
Texas 14
California 13
New York 12
Florida 12
Pennsylvania 11
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Clinical Trial Progress for rivastigmine

Clinical Trial Phase

Clinical Trial Phase for rivastigmine
Clinical Trial Phase Trials
Phase 4 35
Phase 3 30
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for rivastigmine
Clinical Trial Phase Trials
Completed 74
Terminated 10
Recruiting 10
[disabled in preview] 7
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Clinical Trial Sponsors for rivastigmine

Sponsor Name

Sponsor Name for rivastigmine
Sponsor Trials
Novartis 21
Novartis Pharmaceuticals 15
University of Maryland, Baltimore 4
[disabled in preview] 14
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Sponsor Type

Sponsor Type for rivastigmine
Sponsor Trials
Other 112
Industry 62
NIH 6
[disabled in preview] 5
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