The Addition of Clonidine to 0.2% Ropivacaine for Wound Instillation After Minor Lower Abdominal Surgery in Children
Completed
Children's Hospital of Eastern Ontario
Phase 2
2009-09-01
The current study will compare the effects on postoperative pain relief of "freezing"
(ropivacaine 0.2 %) alone and in combination with clonidine for a nerve block in children
undergoing hernia repair. The researchers anticipate that the addition of clonidine to
"freezing" will result in prolongation of postoperative pain relief in children undergoing
hernia repair compared to "freezing" used alone.
Evaluation of Efficacy of Lumbar Plexus Bloc After Hip Surgery
Completed
University Hospital, Angers
N/A
2001-09-01
Compare lumbar plexus block with ropivacaine 0.475%, 0.4 ml/kg to saline. Each group
randomized, includes 30 patients. block performed preoperatively Surgery under general
anesthesia. Postoperative evaluation of pain (VAS) as first endpoint, and also morphine
consumption via PCA device. Follow-up : 24h.
Expectation : sizeable reduction of pain with block, of duration.
Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction
Completed
International Anesthesia Research Society (IARS)
Phase 3
2003-08-01
Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are common and important
disorders of pregnancy. Both disorders are associated with an impairment of uteroplacental
blood flow (UPBF). No effective therapy has been identified to reliably improve UPBF in these
patients and typically, obstetric management involves interventional delivery, particularly
problematic when remote from term. This study assess the hypothesis that epidural local
anesthetics may improve UPBF in these patients.
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