Sibutramine to Reduce Weight Gain and Improve Smoking Cessation Rates
Completed
National Heart, Lung, and Blood Institute (NHLBI)
N/A
2002-09-01
The purpose of this study is to determine if sibutramine will decrease post-cessation weight
gain and cigarette smoking in overweight and obese smokers who quit smoking.
Sibutramine to Reduce Weight Gain and Improve Smoking Cessation Rates
Completed
University of Tennessee
N/A
2002-09-01
The purpose of this study is to determine if sibutramine will decrease post-cessation weight
gain and cigarette smoking in overweight and obese smokers who quit smoking.
The Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I Disorder
Completed
Eli Lilly and Company
Phase 4
2001-04-01
Olanzapine is currently marketed for the treatment of schizophrenia and acute manic episodes
with bipolar 1 disorder. This Anti-obesity Agent is currently marketed for the management of
obesity. In this study, the Anti-obesity Agent is being tested to see if it can treat weight
gain that may be associated with taking olanzapine.
The purposes of this study are to determine the safety of olanzapine when given in
combination with the Anti-obesity Agent and any side effects that might be associated with it
and whether weight-gain agent can help treat weight gain that may be associated with taking
olanzapine.
A Study Of 6-Month Duration To Evaluate The Weight Loss Effect Of Various Doses Of CP-945,598 In Obese Subjects
Completed
Pfizer
Phase 2/Phase 3
2005-03-01
To evaluate the effect of 6-month administration of CP-945,598 on:
- weight loss and waist circumference,
- blood pressure, cholesterol, glucose
- other biochemical variables like insulin, leptin, ghrelin, adiponectin, PAI 1, TNF-α
and hsCRP
- the relationship between the concentration of the drug on the blood and the above
parameters
- physical and psychosocial functioning, weight related symptoms, treatment satisfaction,
appetite/hunger/satiety/craving and mood, anxiety, anhedonia and depression
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