CLINICAL TRIALS PROFILE FOR SILVER SULFADIAZINE
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All Clinical Trials for silver sulfadiazine
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00156988 ↗ | The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns | Completed | Dutch Burns Foundation | Phase 4 | 2004-03-01 | The objective of the proposed study is to assess whether the application of flammacerium for 2 days is as good as, or even better than, the application of flammacerium for 10 days regarding woundhealing in partial thickness burns. |
| NCT00156988 ↗ | The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns | Completed | Association of Dutch Burn Centres | Phase 4 | 2004-03-01 | The objective of the proposed study is to assess whether the application of flammacerium for 2 days is as good as, or even better than, the application of flammacerium for 10 days regarding woundhealing in partial thickness burns. |
| NCT00641433 ↗ | Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails | Unknown status | Rosalind Franklin University of Medicine and Science | N/A | 2005-11-01 | This study's purpose is to prospectively determine whether topical therapy with an oxidized regenerated cellulose collagen-silver compound is more effective than the current standard of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty adult patients with ingrown toenails will be recruited. Each patient will randomly be assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the novel collagen-silver compound to their nail bed daily, following removal of the ingrown portion of nail. Patients will return for follow up visits weekly, until healing has occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and inflammatory changes surrounding the nail border. |
| NCT00798083 ↗ | Neuropathic Pain Caused by Radiation Therapy | Completed | British Columbia Cancer Agency | Phase 3 | 2008-04-01 | To investigate if topical amitriptyline 2%, ketamine 1%, and lidocaine 5% in pluronic lecitine organogel (AKL in PLO gel) can improve management of neuropathic pain from radiation skin reactions adjunctively or better than standard treatment. |
| NCT01297400 ↗ | Phase 2, Open Label, Randomized, Active Controlled Pilot Study MW-III vs Silver Sulfadiazine Second Degree Thermal Burns | Not yet recruiting | Skingenix, Inc. | Phase 2 | 2022-01-12 | To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" in second-degree thermal burns |
| NCT01439074 ↗ | Mepilex Ag Versus Silver Sulfadiazine in Children and Adults With Burn Injuries. | Completed | Molnlycke Health Care AB | N/A | 2011-09-01 | The purpose is to compare time to healing using absorbent foam silver dressing (Mepilex Ag) compared to a silver sulfadiazine (SSD) 1% cream in the treatment of partial thickness burn injuries.284 in-patients in 8-12 centres in China will be evaluated. Treatment period will be up to 4 weeks with either Mepilex Ag or SSD. |
| NCT01553708 ↗ | Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound | Completed | National Science and Technology Development Agency, Thailand | Phase 2/Phase 3 | 2011-12-01 | Partial thickness burn wounds are most likely to heal within 2-3 weeks mainly by mechanism of epithelialization. However, it depends on the depth of the wounds and patient condition. Infection is one of the most common complications causing delay in wound healing which might affect to quality of patient's life. Generally, the standard treatment of partial thickness burn wound is topical 1% silver sulfadiazine cream. Previous studies had been reported the broad spectrum antimicrobial activity of silver sulfadiazine cream but it did not demonstrate the accelerating effect of wound healing. Therefore, the combination of substance which can promote wound healing to topical silver sulfadiazine cream might benefit for partial thickness burn wound treatment. The objective of this study was to compare the results of partial thickness burn wound treatment at burn unit, Siriraj hospital with topical cream containing 1% silver sulfadiazine plus 6% epidermal growth factor (EGF) and 1% silver zinc sulfadiazine. The demographic data (age, sex, %body surface area burn), time of wound closure, pain and itching, dose and type of pain and itching medication, adverse effect of topical medication, some laboratory results and cost of expenses. This is the prospective, double blinded, randomize-controlled study. The sample sizes were partial thickness burn wound patients who were treated at burn unit, Siriraj hospital. Patients were allocated into 2 groups receiving treatment with either topical silver sulfadiazine plus EGF or silver zinc sulfadiazine. All parameter data were analyzed with repeated measure ANOVA and independent t-test. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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