CLINICAL TRIALS PROFILE FOR SODIUM MONOFLUOROPHOSPHATE
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All Clinical Trials for sodium monofluorophosphate
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00708097 ↗ | In Situ Caries Efficacy of Fluoride Toothpastes | Completed | GlaxoSmithKline | Phase 3 | 2008-04-01 | This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model |
NCT00708123 ↗ | In Situ Caries of Fluoride Toothpastes | Completed | GlaxoSmithKline | Phase 3 | 2007-11-01 | This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model. |
NCT00759031 ↗ | Investigation of Dental Plaque and Gingival Index | Completed | Colgate Palmolive | Phase 3 | 2008-02-01 | Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method. |
NCT01589458 ↗ | Fluoride Availability in Saliva After Use of Sodium Fluoride or Monofluorophosphate Toothpastes | Completed | University of Campinas, Brazil | Phase 1 | 2011-08-01 | Considering the widespread use of sodium fluoride (NaF) and monofluorophosphate (MFP) based toothpastes, the present study aim to evaluate F availability in saliva after use of the top-selling Brazilian toothpastes. In a blind, crossover clinical trial study, volunteers will brush their teeth with one of the following toothpastes: 1) non-fluoride toothpaste (negative control group); 2) NaF/silica based toothpaste 3)MFP/calcium carbonate based toothpaste. After brushing, a rinse with purified water will be performed. Unstimulated saliva will be collected before and up to 60 min after brushing. Ionic fluoride and total soluble fluoride (corresponding to the sum of fluoride as ion and as MFP) will be determined after acid treatment of salivary samples to hydrolyze MFP. Fluoride will be determined using an ion selective electrode. |
NCT01592851 ↗ | Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity | Completed | GlaxoSmithKline | Phase 3 | 2012-04-01 | A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period. |
NCT01592864 ↗ | The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity | Completed | GlaxoSmithKline | Phase 3 | 2012-03-01 | A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period. |
NCT01657877 ↗ | Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice | Completed | GlaxoSmithKline | Phase 2 | 2012-05-01 | In situ study to compare treatment effect on enamel remineralization potential, measured by surface microhardness recovery (SMHR) and Enamel Fluoride Uptake (EFU). The study will explore the efficacy of an experimental sodium monofluorophosphate (SMFP) dentifrice containing calcium sodium phosphosilicate (CSP) in comparison to an experimental SMFP only dentifrice. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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