Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops
Completed
Santen Oy
Phase 3
2008-01-01
The purpose of this study is to investigate if changes in ocular signs and symptoms occur in
patients with ocular hypertension or glaucoma when they switch from latanoprost 0.005%
(Xalatan) to preservative free Tafluprost eye drops.
Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation
Completed
Santen Oy
Phase 3
2005-09-01
The objective of this study is to investigate the pharmacodynamics (as expressed in
intraocular pressure [IOP]) of two formulations of tafluprost 0.0015% eyedrops (preserved and
unpreserved) in patients with open-angle glaucoma or ocular hypertension.
The primary aim of this study is to show that IOP reduction between the two formulations is
equivalent at the end of the 4 week treatment period.
Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
Completed
Alcon Research
Phase 4
2009-09-01
The purpose of this study is to assess the safety and efficacy of Travoprost 0.004% and
Tafluprost 0.0015% in patients with primary open angle glaucoma or ocular hypertension when
both medications are administered in the evening.
Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)
Completed
Merck Sharp & Dohme Corp.
Phase 3
2010-01-06
This study was to compare the safety and efficacy of the preservative-free formulation of
0.0015% MK2452 (tafluprost) and preservative-free 0.5% timolol maleate in patients with
open-angle glaucoma and ocular hypertension. This study was to demonstrate that the
preservative-free formulation of 0.0015% tafluprost is non-inferior to preservative-free 0.5%
timolol maleate.
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