CLINICAL TRIALS PROFILE FOR TEDUGLUTIDE

All Clinical Trials for teduglutide

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00081458 ↗	Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome	Completed	Shire	Phase 3	2004-05-25	The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of teduglutide compared with placebo in subjects with parenteral nutrition (PN)-dependent short bowel syndrome (SBS).
NCT00172185 ↗	Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)	Completed	Shire	Phase 3	2005-01-10	The purpose of this clinical study is to evaluate the long-term safety and efficacy of daily administration of teduglutide.
NCT00308438 ↗	Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008	Completed	Shire	Phase 2	2004-03-01	The purpose of the study is to determine whether an investigational compound, ALX-0600, is safe and effective in treating Crohn's Disease.
NCT00798967 ↗	Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects	Completed	Nycomed	Phase 3	2008-11-25	Teduglutide is an investigative medicine being evaluated as a possible treatment for people with parenteral nutrition (PN) dependent Short Bowel Syndrome (SBS). Teduglutide is similar to a protein the body makes. When people have SBS, their bodies do not make enough of the protein and they have trouble getting nutrients and fluids from the food they eat and drink. This study was designed to provide evidence of efficacy, safety, and tolerability of teduglutide 0.05 mg/kg daily in SBS subjects.

Clinical Trial Conditions for teduglutide

Condition Name

Condition Name for teduglutide
Intervention	Trials
Short Bowel Syndrome	18
Hyperlipidemias	4
Healthy Volunteers	2
Hepatic Impairment	1

Condition MeSH

Condition MeSH for teduglutide
Intervention	Trials
Syndrome	18
Short Bowel Syndrome	18
Hyperlipoproteinemias	4
Hyperlipidemias	4

Clinical Trial Locations for teduglutide

Trials by Country

Trials by Country for teduglutide
Location	Trials
United States	110
Canada	22
Japan	18
United Kingdom	16
Germany	10

Trials by US State

Trials by US State for teduglutide
Location	Trials
New York	10
Ohio	9
California	7
Pennsylvania	7
Texas	6

Clinical Trial Progress for teduglutide

Clinical Trial Phase

Clinical Trial Phase for teduglutide
Clinical Trial Phase	Trials
Phase 4	3
Phase 3	17
Phase 2/Phase 3	4

Clinical Trial Status

Clinical Trial Status for teduglutide
Clinical Trial Phase	Trials
Completed	28
Active, not recruiting	3
Not yet recruiting	2

Clinical Trial Sponsors for teduglutide

Sponsor Name

Sponsor Name for teduglutide
Sponsor	Trials
Shire	21
Takeda	4
University Health Network, Toronto	4

Sponsor Type

Sponsor Type for teduglutide
Sponsor	Trials
Industry	32
Other	18
NIH	2