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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR TENOFOVIR ALAFENAMIDE FUMARATE

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All Clinical Trials for tenofovir alafenamide fumarate

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00036634 ↗	A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients	Completed	Gilead Sciences	Phase 1/Phase 2	2002-03-01	This study evaluated two doses of tenofovir alafenamide versus tenofovir disoproxil fumarate (tenofovir DF).
NCT01497899 ↗	Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive Adults	Completed	Gilead Sciences	Phase 2	2011-12-28	The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (Genvoya®; E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (Stribild®; E/C/F/TDF) FDC in HIV-1 infected, antiretroviral treatment-naive adults.
NCT01565850 ↗	D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults	Completed	Gilead Sciences	Phase 2	2012-04-01	This study is to evaluate the safety and efficacy darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) fixed dose combination (FDC) tablet versus darunavir (DRV)+cobicistat (COBI)+emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in HIV-1 infected, antiretroviral treatment-naive adults as determined by the achievement of HIV-1 RNA < 50 copies/mL at Week 24.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for tenofovir alafenamide fumarate

Condition Name

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Condition Name for tenofovir alafenamide fumarate
Intervention	Trials
Hiv	14
Chronic Hepatitis b	12
HIV Infections	10
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Condition MeSH

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Condition MeSH for tenofovir alafenamide fumarate
Intervention	Trials
Hepatitis B	30
Hepatitis	26
HIV Infections	20
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Clinical Trial Locations for tenofovir alafenamide fumarate

Trials by Country

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Trials by Country for tenofovir alafenamide fumarate
Location	Trials
United States	373
China	75
Canada	54
United Kingdom	23
France	22
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Trials by US State

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Trials by US State for tenofovir alafenamide fumarate
Location	Trials
California	26
Florida	21
Texas	19
New York	19
Michigan	18
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Clinical Trial Progress for tenofovir alafenamide fumarate

Clinical Trial Phase

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Clinical Trial Phase for tenofovir alafenamide fumarate
Clinical Trial Phase	Trials
Phase 4	22
Phase 3	28
Phase 2	11
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Clinical Trial Status

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Clinical Trial Status for tenofovir alafenamide fumarate
Clinical Trial Phase	Trials
Completed	31
Recruiting	24
Not yet recruiting	14
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Clinical Trial Sponsors for tenofovir alafenamide fumarate

Sponsor Name

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Sponsor Name for tenofovir alafenamide fumarate
Sponsor	Trials
Gilead Sciences	35
Third Affiliated Hospital, Sun Yat-Sen University	5
National Institute of Allergy and Infectious Diseases (NIAID)	4
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Sponsor Type

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Sponsor Type for tenofovir alafenamide fumarate
Sponsor	Trials
Other	83
Industry	45
NIH	5
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