Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
Completed
Memorial Sloan Kettering Cancer Center
Phase 1
2004-09-01
The purpose of this research is to understand how some of the drugs commonly used in
anesthesia impair memory. We are particularly interested in whether the emotion associated
with a memory influences how well these drugs are able to block memory. We are studying four
commonly used drugs-propofol, thiopental, midazolam, and dexmedetomidine, all of which may
have slightly differing effects. We will also study an inactive substance, called a placebo,
that should have no effect. The results of this study will provide information that will be
useful in understanding how memory works, how these drugs affect memory, and possibly why
some people don't have their memory blocked as easily as others.
Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery
Completed
General Hospital Dubrovnik
N/A
2007-09-01
Two groups of patients are going to have abdominal surgery with low-flow general anaesthesia.
Group A (sevoflurane group, experimental group) will use volatile anaesthetic sevoflurane.
Group B (isoflurane group, control group) will use volatile anaesthetic isoflurane. It will
be observed differences between volatile anaesthetic sevoflurane and volatile anaesthetic
isoflurane for providing low-flow general anaesthesia for abdominal surgery. Duration of this
randomised controled trial will be approximately 2 months. Estimated sample size will be 82
persons (41 in sevoflurane group and 41 in isoflurane group).
The Effect of Ketamine on Interleukin-6 Synthesis in Hepatic Resections Requiring Temporary Porto-arterial Occlusion
Completed
Hospital Italiano de Buenos Aires
Phase 4
2001-06-01
The purpose of this study is to determine whether ketamine is effective to inhibit
interleukin 6 synthesis in hepatic resections requiring temporary porto-arterial occlusion.
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