CLINICAL TRIALS PROFILE FOR TIZANIDINE HYDROCHLORIDE
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All Clinical Trials for tizanidine hydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00047580 ↗ | Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe | Completed | Elan Pharmaceuticals | Phase 3 | 2002-06-01 | This study is being conducted to compare the impact of somnolence (sleepiness) on cognition (awareness) as well as the safety and effectiveness of tizanidine hydrochloride capsules versus Zanaflex® (tizanidine hydrochloride tablets) taken while in the fed state (just after a meal) and in the fasted state (before a meal) in patients with moderate to severe spasticity. |
| NCT00178646 ↗ | Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity | Completed | Allergan | Phase 4 | 2002-01-01 | The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke. |
| NCT00178646 ↗ | Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity | Completed | The University of Texas Health Science Center, Houston | Phase 4 | 2002-01-01 | The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke. |
| NCT00228267 ↗ | Propofol Injection for Daily Headache | Completed | University of Alberta | Phase 2 | 2004-09-01 | Hypothesis A single subanesthetic dose of propofol will result in improved pain and quality of life for the next 30 days in persons with chronic daily headache (CDH) Specific objectives To measure the effect of a single infusion of propofol at 40 mcg / kg / minute over 60 mins on headache-related quality of life (measured by the Headache Disability Index) and on headache severity (measured by the Headache Index) in subjects with chronic daily headache over 30 days45-47 |
| NCT00287157 ↗ | Pilot, Proof-of-Concept Study of Sublingual Tizanidine in Children With Chronic Traumatic Brain Injury (TBI) | Completed | Teva GTC | Phase 1 | 2006-12-01 | Nightly administration of a unique, sublingual (under the tongue) formulation of tizanidine, a known anti-spasticity medication, has been shown in a previous study to improve sleep and next-day functioning in CP (cerebral palsy) patients. It is hypothesized that this improvement in sleep efficiency (i.e.,fewer wake episodes, longer time asleep, etc.) with resulting improvement in quality-of-life (i.e.,improvements in next-day functioning, cognition and movement) may also be seen in a similar patient population, i.e., children with traumatic brain injury (TBI). |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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